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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges

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AI BioDesign: advancing biology and accelerating evolution
A bold and innovative collaboration between the Allen Institute, Fred Hutch Cancer Center, and the University of Washington, AI BioDesign will engineer and build new biomolecules that don’t exist in nature to help find new treatments for disease.
ai biodesign
video

AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges
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genetics and wiring play a role in Alzheimer’s disease
UC San Francisco study that used Allen Institute’s Human Brain Atlas could lead to better treatments and therapies
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the battle within
A scientist’s mission to conquer the disease that may one day conquer him
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multimedia

cancer research opens new window into battle against viruses
Scientists discover why multiple myeloma patients remain vulnerable to infection even after beating the cancer, and the findings could help develop better vaccines
immunology
news

finding Alzheimer's targets, one cell type at a time
How Shanahan Fellow Iris Stone used her Alzheimer's research and business savvy to chart a path into biotech
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ketamine increases neuroplasticity in female mice but not in males
The surprising finding could help scientists develop better treatments for depression
brain science
news

rogue DNA can move from cell to cell and change how they function
Scientists used Allen Institute cell lines to discover an important new way that cells trade genetic material
cell science
news

Karel Svoboda elected to the Washington State Academy of Sciences
Svoboda’s work has advanced our understanding of the neural mechanisms of learning, movement, and complex brain behavior
neural dynamics
news

SciShots: amber waves of brain
New video illustrates how neural activity in a mouse brain travels in aesthetically pleasing waves and spirals
brain science
science images
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Seattle scientists launch $95 million AI biology effort
The Allen Institute, University of Washington, and Fred Hutch Cancer Center are launching a $95 million effort to use AI to design biology that doesn’t exist in nature. Called AI BioDesign and led scientifically by Nobel laureate David Baker and genome scientist Jay Shendure, the initiative will use AI models to propose new DNA sequences and biological molecules.

AI learns nature’s code: Allen Institute, UW and Fred Hutch launch $95M open science initiative
Three of Seattle’s top scientific institutions are launching a nearly $95 million research initiative that will generate data and train AI models to design proteins and genes that don’t exist in nature — sharing the results freely to help others develop new medicines and materials.

‘It’s going to come quicker than we think’: Parkinson’s advocate shares hope for treatment as Allen Institute launches AI-powered initiative
The institute has launched the Brain Health Accelerator, an international collaboration involving about 30 research organizations that will use artificial intelligence, human brain tissue and advanced cellular mapping to better understand diseases including Parkinson’s, Alzheimer’s disease, ALS, Huntington’s disease and Lewy body dementia.

Allen Institute sets sights on treatments for five brain diseases
The Brain Health Accelerator program aims to harness single-cell transcriptomics and cell-type-specific genetic tools to develop treatments for Alzheimer’s, Huntington’s and Parkinson’s diseases, Lewy body dementia and ALS.
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