We are human. We are the next frontier.

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The Allen Institute is fiercely committed to solving some of the biggest mysteries of bioscience, researching the unknown of human biology, in the brain, the human cell, and the immune system. At the same time, we are pushing the frontiers of bioscience to continue to explore the edges of scientific discovery.

Our Diversity, Equity and Inclusion commitment

Cell by cell, scientists are building a high-resolution map of brain changes in Alzheimer’s disease

There is every reason to believe that Alzheimer's disease has its roots in specific types of brain cells. That's why Allen Institute scientists, together with collaborators at UW Medicine and Kaiser Permanente Washington Health Research Institute and with support from the National Institute on Aging, are taking a new kind of approach, cell by cell, to understand the disease. They've just released their first dataset, from 1.2M brain cells, that hints at the kinds of cells that die off or change in the neurodegenerative disease.

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News Highlights

Read more about the Allen Institute in the news and stories highlighting accomplishments and partnerships. 

News

DNA’s molecular wrinkles: Why you might be older or younger than you think

August 3, 2022

‘Epigenetic clocks’ vary with disease and even by organ, but scientists are still trying to understand why 

News

DNA Typewriter keeps a record of cells’ long histories

July 21, 2022

Molecular recording device could be used to trace cell-by-cell growth of an entire animal

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SciShots: The 3D network inside a mouse’s brain

July 8, 2022

Scientists are piecing together the puzzle of the brain using light-sheet microscopy

News

Out of Balance | Sarah’s experience with multiple myeloma

June 8, 2022

Sarah Kaufmann-Fink was diagnosed with cancer as a college student. 17 years and one relapse later, she’s pushing for more research.  

News

A new open-access portal for human immunology data and tools

June 1, 2022

The Human Immune System Explorer offers an inside view into ongoing research on human health and disease

Our Impact on Science, and our World

Our knowledge, data and tools have been a catalyst across the world, allowing other scientists to accelerate their research and advance our understanding of human health and disease.

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See how researcher Kathryn McGuckin Wuertz is trying to understand the relationship between infectious diseases and neurological diseases
Researchers have succeeded in growing the most lifelike human skin in the lab to date. Allen Institute for Cell Science cell lines formed the basis for the human skin organoids.


Our Revolutionary Scientific Resources

Atlases that map the brain, a “periodic table” of cell types in the brain, and an observatory allowing for a large-scale approach to understanding the brain and watching neurons fire in real time, are all available on Allen Brain Map.
We created the first predictive and integrated 3D cell explorer and a collection of human stem cells to help improve the collective understanding of human cells in health—and ultimately disease, all available on the Allen Cell Explorer.

Lab Notes — a podcast from the Allen Institute

 

May 26, 2022 — Can we put a number on human consciousness? Neuroscientist Christof Koch is leading an effort to build a consciousness meter that could have real-world applications to determine whether coma patients are in a true vegetative state. Christof joined Lab Notes to talk about the science of consciousness, what psychedelic drugs have to do with consciousness, and how this new project could one day have applications in hospitals and clinics.

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