We are human. We are the next frontier.

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The Allen Institute is fiercely committed to solving some of the biggest mysteries of bioscience, researching the unknown of human biology, in the brain, the human cell, and the immune system. At the same time, we are pushing the frontiers of bioscience to continue to explore the edges of scientific discovery.

Our Diversity, Equity and Inclusion commitment

Cell by cell, scientists are building a high-resolution map of brain changes in Alzheimer’s disease

There is every reason to believe that Alzheimer's disease has its roots in specific types of brain cells. That's why Allen Institute scientists, together with collaborators at UW Medicine and Kaiser Permanente Washington Health Research Institute and with support from the National Institute on Aging, are taking a new kind of approach, cell by cell, to understand the disease. They've just released their first dataset, from 1.2M brain cells, that hints at the kinds of cells that die off or change in the neurodegenerative disease.

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News Highlights

Read more about the Allen Institute in the news and stories highlighting accomplishments and partnerships. 

News

Mapping the whole human brain: Allen Institute to lead global collaboration

September 22, 2022

NIH BRAIN Initiative to fund primate brain atlases, maps of developing mouse brain, coordination and knowledge sharing, and brain function research

News

SciShots: The brain’s mysterious, multipurpose immune system

September 16, 2022

Microglial cells act as the brain’s waste disposal when healthy — can they be manipulated to protect against disease? 

Video

Opening up about open science

September 15, 2022

In five words, more or less, what does open science mean to you? We asked our talented teams at the Allen Institute.

Video

Look in the labs

September 12, 2022

Get a behind the scenes look at the specialized laboratories and talented teams who make our work possible here at the Allen Institute. 

News

23 interns, 4 coffee machines, 1 summer: Through the eyes of this year’s cohort of budding science professionals

August 26, 2022

Allen Institute welcomes interns on-site for the first time since 2019 — these are some of their stories 

Podcast

Lab Notes | Bees suffer from social isolation too

August 25, 2022

Neuroscientist Z Yan Wang investigated how social isolation impacted young bumblebees, and it looks like they grow up to be a little ‘socially awkward.’

Our Impact on Science, and our World

Our knowledge, data and tools have been a catalyst across the world, allowing other scientists to accelerate their research and advance our understanding of human health and disease.

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See how researcher Kathryn McGuckin Wuertz is trying to understand the relationship between infectious diseases and neurological diseases
Researchers have succeeded in growing the most lifelike human skin in the lab to date. Allen Institute for Cell Science cell lines formed the basis for the human skin organoids.


Our Revolutionary Scientific Resources

Atlases that map the brain, a “periodic table” of cell types in the brain, and an observatory allowing for a large-scale approach to understanding the brain and watching neurons fire in real time, are all available on Allen Brain Map.
We created the first predictive and integrated 3D cell explorer and a collection of human stem cells to help improve the collective understanding of human cells in health—and ultimately disease, all available on the Allen Cell Explorer.

Lab Notes — a podcast from the Allen Institute

 

May 26, 2022 — Can we put a number on human consciousness? Neuroscientist Christof Koch is leading an effort to build a consciousness meter that could have real-world applications to determine whether coma patients are in a true vegetative state. Christof joined Lab Notes to talk about the science of consciousness, what psychedelic drugs have to do with consciousness, and how this new project could one day have applications in hospitals and clinics.

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