We are human. We are the next frontier.

Learn More

The Allen Institute is fiercely committed to solving some of the biggest mysteries of bioscience, researching the unknown of human biology, in the brain, the human cell, and the immune system. At the same time, we are pushing the frontiers of bioscience to continue to explore the edges of scientific discovery.

Our Diversity, Equity and Inclusion commitment

Cell by cell, scientists are building a high-resolution map of brain changes in Alzheimer’s disease

There is every reason to believe that Alzheimer's disease has its roots in specific types of brain cells. That's why Allen Institute scientists, together with collaborators at UW Medicine and Kaiser Permanente Washington Health Research Institute and with support from the National Institute on Aging, are taking a new kind of approach, cell by cell, to understand the disease. They've just released their first dataset, from 1.2M brain cells, that hints at the kinds of cells that die off or change in the neurodegenerative disease.

Learn More

News Highlights

Read more about the Allen Institute in the news and stories highlighting accomplishments and partnerships. 

News

How do human neurons respond to psychedelics?

November 12, 2022

Neuroscientists send live human brain samples on a trip to glean insights into consciousness, therapy for depression and anxiety  

News

SciShots: Illuminating a mysterious brain structure

November 11, 2022

Neuroscientists are shedding literal light on the mouse claustrum, a tiny part of the brain with an outsized number of connections 

News

These brain cells named for stars contribute to Alzheimer’s

November 3, 2022

Mouse study reveals many new types of cells known as astrocytes and narrows their role in neurodegenerative disease 

News

SciShots: Brain-o-lantern

October 31, 2022

Quality control spies a spooky brain

News

Allen Institute names Chris Beaudoin as Chief Operations Officer

October 21, 2022

Beaudoin brings more than two decades of leadership experience in the healthcare field to the Institute

News

SciShots: The Brain’s Cleanup Crew and Paramedics

October 14, 2022

The shape-shifting microglia play a vital role in maintaining brain health

Our Impact on Science, and our World

Our knowledge, data and tools have been a catalyst across the world, allowing other scientists to accelerate their research and advance our understanding of human health and disease.

View More Impact Stories

 

See how researcher Kathryn McGuckin Wuertz is trying to understand the relationship between infectious diseases and neurological diseases
Researchers have succeeded in growing the most lifelike human skin in the lab to date. Allen Institute for Cell Science cell lines formed the basis for the human skin organoids.


Our Revolutionary Scientific Resources

Atlases that map the brain, a “periodic table” of cell types in the brain, and an observatory allowing for a large-scale approach to understanding the brain and watching neurons fire in real time, are all available on Allen Brain Map.
We created the first predictive and integrated 3D cell explorer and a collection of human stem cells to help improve the collective understanding of human cells in health—and ultimately disease, all available on the Allen Cell Explorer.

Reward is essential for life. Our brains flood with feel-good chemicals when we learn, eat, have sex. But these essential brain circuits are hijacked in drug addiction. Neuroscientists at the Allen Institute and the University of North Carolina are working to crack the biology of reward and addiction. Hear about their work and their hopes for the future of treating addiction in the latest episode of Lab Notes, a podcast from the Allen Institute.

Click the logos to learn more about our scientific divisions