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AI BioDesign: advancing biology and accelerating evolution

A bold and innovative collaboration between the Allen Institute, Fred Hutch Cancer Center, and the University of Washington, AI BioDesign will engineer and build new biomolecules that don’t exist in nature to help find new treatments for disease.

September 3, 2026
0 min read
ai biodesign/ beyond human imagination
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AI BioDesign harnesses the power of artificial intelligence and experimental biology to advance human health and solve global challenges. A bold and innovative collaboration between the Allen Institute, Fred Hutch Cancer Center, and the University of Washington, AI BioDesign will engineer and build new biomolecules that don’t exist in nature to help find new treatments for disease. The Seattle-based research initiative leverages the combined expertise of global leaders in bioscience, innovation, and technology.

in this article

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authors

Erik Dinnel
Senior Producer

contributors

Jay Shendure
lead scientific director of AI BioDesign, scientific director of the UW Medicine Brotman Baty Institute for Precision Medicine, scientific director of the Seattle Hub for Synthetic Biology, and a Howard Hughes Medical Institute investigator
David Baker
lead scientific director, AI BioDesign; director, UW Medicine Institute for Protein Design; Howard Hughes Medical Institute investigator

advancing biology’s design capabilities/

What if the next breakthrough for human health, climate resilience, or clean energy isn’t waiting to be found in nature. What if it's waiting to be designed?

Today, we’re launching AI BioDesign, a new accelerator from the Allen Institute in collaboration with UW Medicine and Fred Hutch, with support from Fund for Science and Technology. AI BioDesign harnesses the power of artificial intelligence and experimental biology to explore what biology could become: new proteins, genes, and biological systems beyond what evolution has already produced. The Seattle-based research initiative leverages the combined expertise of global leaders in bioscience, innovation, and technology.

This is biology beyond evolution: an open, experimentally grounded effort to design tools for problems we cannot yet solve.

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about the allen institute

Allen Institute is a 501(c)(3) tax exempt organization dedicated to accelerating science for a healthier world. Through large-scale, multidisciplinary research initiatives, the Institute generates foundational knowledge, data, tools, and models that are shared openly with the world to advance our understanding of life and health. Founded by Jody Allen and the late Paul G. Allen, Allen Institute is supported primarily by Fund for Science and Technology.

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AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges
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