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education
exploring cell division and cell structures through open data

an introduction to mitosis using real cell images

Explore mitosis through comparing cell diagrams to real stem cell images.

resource type / 
Lesson Plan
published / June 29, 2026
education level / 
Undergraduate
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lessons & resources in this unit

interactive 3D model of cell division
identifying mitotic stages in a large image dataset
exploring organelle localization throughout mitosis
introduction to the Cell Feature Explorer (CFE)
quantitative analysis of stem cell images

in this lesson

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contributors

Madison Meuler
Education and Engagement Specialist II
Claire Weichselbaum
Education & Engagement Specialist III
Kaitlyn Casimo
Senior Manager, Education & Engagement
Gideon Dunster
Scientific Program Manager
Carlos Goller
Teaching Professor, North Carolina State University

This lesson walks students through real images of fluorescently tagged human-induced pluripotent stem cells (hiPSCs) as they undergo mitosis. The lesson contains embedded in-class polling questions and an associated worksheet that asks students to identify the stages of mitosis in both cell diagrams and real cell images.

learning objectives/

  • Describe how the process of mitosis fits into the larger cell cycle  ‍
  • Evaluate mechanisms that help regulate the process of mitosis
  • ‍Apply key mitosis vocabulary such as chromosome, chromatin, and sister chromatids
  • ‍Summarize and illustrate the stages of mitosis
  • ‍Evaluate real microscopy images of cells undergoing mitosis
  • ‍Categorize the images based on which phase of mitosis they depict

materials

instructor guide
slide deck
worksheet
worksheet key
all resources

funding acknowledgement/

The development of this lesson was supported by the National Science Foundation under Award Number 2236366. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Science Foundation.

‍

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Lesson(s)
exploring cell division and cell structures through open data
Learn foundational concepts in cell structures and mitosis with real images of human cells
Lesson(s)
an introduction to mitosis using real cell images
Explore mitosis through comparing cell diagrams to real stem cell images.
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