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publication / 2021
A multimodal cell census and atlas of the mammalian primary motor cortex
Nature
Brain Science
MindScope

BRAIN Initiative Cell Census Network (BICCN)

publication / 2021
A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex
Nature
Brain Science
MindScope

Zizhen Yao, Hanqing Liu, Fangming Xie, Stephan Fischer, Ricky S. Adkins, Andrew I. Aldridge, Seth A. Ament, Anna Bartlett, M. Margarita Behrens, Koen Van den Berge, Darren Bertagnolli, Hector Roux de Bézieux, Tommaso Biancalani, A. Sina Booeshaghi, Héctor Corrada Bravo, Tamara Casper, Carlo Colantuoni, Jonathan Crabtree, Heather Creasy, Kirsten Crichton, Megan Crow, Nick Dee, Elizabeth L. Dougherty, Wayne I. Doyle, Sandrine Dudoit, Rongxin Fang, Victor Felix, Olivia Fong, Michelle Giglio, Jeff Goldy, Mike Hawrylycz, Brian R. Herb, Ronna Hertzano, Xiaomeng Hou, Qiwen Hu, Jayaram Kancherla, Matthew Kroll, Kanan Lathia, Yang Eric Li, Jacinta D. Lucero, Chongyuan Luo, Anup Mahurkar, Delissa McMillen, Naeem M. Nadaf, Joseph R. Nery, Thuc Nghi Nguyen, Sheng-Yong Niu, Vasilis Ntranos, Joshua Orvis, Julia K. Osteen, Thanh Pham, Antonio Pinto-Duarte, Olivier Poirion, Sebastian Preissl, Elizabeth Purdom, Christine Rimorin, Davide Risso, Angeline C. Rivkin, Kimberly Smith, Kelly Street, Josef Sulc, Valentine Svensson, Michael Tieu, Amy Torkelson, Herman Tung, Eeshit Dhaval Vaishnav, Charles R. Vanderburg, Cindy van Velthoven, Xinxin Wang, Owen R. White, Z. Josh Huang, Peter V. Kharchenko, Lior Pachter, John Ngai, Aviv Regev, Bosiljka Tasic, Joshua D. Welch, Jesse Gillis, Evan Z. Macosko, Bing Ren, Joseph R. Ecker, Hongkui Zeng, Eran A. Mukamel

publication / 2021
Cellular anatomy of the mouse primary motor cortex
Nature
Brain Science
MindScope

Rodrigo Muñoz-Castañeda, Brian Zingg, Katherine S. Matho, Xiaoyin Chen, Quanxin Wang, Nicholas N. Foster, Anan Li, Arun Narasimhan, Karla E. Hirokawa, Bingxing Huo, Samik Bannerjee, Laura Korobkova, Chris Sin Park, Young-Gyun Park, Michael S. Bienkowski, Uree Chon, Diek W. Wheeler, Xiangning Li, Yun Wang, Maitham Naeemi, Peng Xie, Lijuan Liu, Kathleen Kelly, Xu An, Sarojini M. Attili, Ian Bowman, Anastasiia Bludova, Ali Cetin, Liya Ding, Rhonda Drewes, Florence D'Orazi, Corey Elowsky, Stephan Fischer, William Galbavy, Lei Gao, Jesse Gillis, Peter A. Groblewski, Lin Gou, Joel D. Hahn, Joshua T. Hatfield, Houri Hintiryan, Junxiang Jason Huang, Hideki Kondo, Xiuli Kuang, Philip Lesnar, Xu Li, Yaoyao Li, Mengkuan Lin, Darrick Lo, Judith Mizrachi, Stephanie Mok, Philip R. Nicovich, Ramesh Palaniswamy, Jason Palmer, Xiaoli Qi, Elise Shen, Yu-Chi Sun, Huizhong W. Tao, Wayne Wakemen, Yimin Wang, Shenqin Yao, Jing Yuan, Huiqing Zhan, Muye Zhu, Lydia Ng, Li I. Zhang, Byung Kook Lim, Michael Hawrylycz, Hui Gong, James C. Gee, Yongsoo Kim, Kwanghun Chung, X. William Yang, Hanchuan Peng, Qingming Luo, Partha P. Mitra, Anthony M. Zador, Hongkui Zeng, Giorgio A. Ascoli, Z. Josh Huang, Pavel Osten, Julie A. Harris, Hong-Wei Dong

publication / 2021
Comparative cellular analysis of motor cortex in human, marmoset and mouse
Nature
Brain Science
MindScope

Trygve E. Bakken, Nikolas L. Jorstad, Qiwen Hu, Blue B. Lake, Wei Tian, Brian E. Kalmbach, Megan Crow, Rebecca D. Hodge, Fenna M. Krienen, Staci A. Sorensen, Jeroen Eggermont, Zizhen Yao, Brian D. Aevermann, Andrew I. Aldridge, Anna Bartlett, Darren Bertagnolli, Tamara Casper, Rosa G. Castanon, Kirsten Crichton, Tanya L. Daigle, Rachel Dalley, Nick Dee, Nikolai Dembrow, Dinh Diep, Song-Lin Ding, Weixiu Dong, Rongxin Fang, Stephan Fischer, Melissa Goldman, Jeff Goldy, Lucas T. Graybuck, Brian R. Herb, Xiaomeng Hou, Jayaram Kancherla, Matthew Kroll, Kanan Lathia, Baldur van Lew, Yang Eric Li, Christine S. Liu, Hanqing Liu, Jacinta D. Lucero, Anup Mahurkar, Delissa McMillen, Jeremy A. Miller, Marmar Moussa, Joseph R. Nery, Philip R. Nicovich, Sheng-Yong Niu, Joshua Orvis, Julia K. Osteen, Scott Owen, Carter R. Palmer, Thanh Pham, Nongluk Plongthongkum, Olivier Poirion, Nora M. Reed, Christine Rimorin, Angeline Rivkin, William J. Romanow, Adriana E. Sedeño-Cortés, Kimberly Siletti, Saroja Somasundaram, Josef Sulc, Michael Tieu, Amy Torkelson, Herman Tung, Xinxin Wang, Fangming Xie, Anna Marie Yanny, Renee Zhang, Seth A. Ament, M. Margarita Behrens, Hector Corrada Bravo, Jerold Chun, Alexander Dobin, Jesse Gillis, Ronna Hertzano, Patrick R. Hof, Thomas Höllt, Gregory D. Horwitz, C. Dirk Keene, Peter V. Kharchenko, Andrew L. Ko, Boudewijn P. Lelieveldt, Chongyuan Luo, Eran A. Mukamel, António Pinto-Duarte, Sebastian Preissl, Aviv Regev, Bing Ren, Richard H. Scheuermann, Kimberly Smith, William J. Spain, Owen R. White, Christof Koch, Michael Hawrylycz, Bosiljka Tasic, Evan Z. Macosko, Steven A. McCarroll, Jonathan T. Ting, Hongkui Zeng, Kun Zhang, Guoping Feng, Joseph R. Ecker, Sten Linnarsson, Ed S. Lein

publication / 2021
Genetic dissection of the glutamatergic neuron system in cerebral cortex
Nature
Brain Science
MindScope

Katherine S. Matho, Dhananjay Huilgol, William Galbavy, Miao He, Gukhan Kim, Xu An, Jiangteng Lu, Priscilla Wu, Daniela J. Di Bella, Ashwin S. Shetty, Ramesh Palaniswamy, Joshua Hatfield, Ricardo Raudales, Arun Narasimhan, Eric Gamache, Jesse M. Levine, Jason Tucciarone, Eric Szelenyi, Julie A. Harris, Partha P. Mitra, Pavel Osten, Paola Arlotta, Z. Josh Huang

publication / 2021
Human neocortical expansion involves glutamatergic neuron diversification
Nature
Brain Science
MindScope

Jim Berg, Staci A. Sorensen, Jonathan T. Ting, Jeremy A. Miller, Thomas Chartrand, Anatoly Buchin, Trygve E. Bakken, Agata Budzillo, Nick Dee, Song-Lin Ding, Nathan W. Gouwens, Rebecca D. Hodge, Brian Kalmbach, Changkyu Lee, Brian R. Lee, Lauren Alfiler, Katherine Baker, Eliza Barkan, Allison Beller, Kyla Berry, Darren Bertagnolli, Kris Bickley, Jasmine Bomben, Thomas Braun, Krissy Brouner, Tamara Casper, Peter Chong, Kirsten Crichton, Rachel Dalley, Rebecca de Frates, Tsega Desta, Samuel Dingman Lee, Florence D'Orazi, Nadezhda Dotson, Tom Egdorf, Rachel Enstrom, Colin Farrell, David Feng, Olivia Fong, Szabina Furdan, Anna A. Galakhova, Clare Gamlin, Amanda Gary, Alexandra Glandon, Jeff Goldy, Melissa Gorham, Natalia A. Goriounova, Sergey Gratiy, Lucas Graybuck, Hong Gu, Kristen Hadley, Nathan Hansen, Tim S. Heistek, Alex M. Henry, Djai B. Heyer, DiJon Hill, Chris Hill, Madie Hupp, Tim Jarsky, Sara Kebede, Lisa Keene, Lisa Kim, Mean-Hwan Kim, Matthew Kroll, Caitlin Latimer, Boaz P. Levi, Katherine E. Link, Matthew Mallory, Rusty Mann, Desiree Marshall, Michelle Maxwell, Medea McGraw, Delissa McMillen, Erica Melief, Eline J. Mertens, Leona Mezei, Norbert Mihut, Stephanie Mok, Gabor Molnar, Alice Mukora, Lindsay Ng, Kiet Ngo, Philip R. Nicovich, Julie Nyhus, Gaspar Olah, Aaron Oldre, Victoria Omstead, Attila Ozsvar, Daniel Park, Hanchuan Peng, Trangthanh Pham, Christina A. Pom, Lydia Potekhina, Ramkumar Rajanbabu, Shea Ransford, David Reid, Christine Rimorin, Augustin Ruiz, David Sandman, Josef Sulc, Susan M. Sunkin, Aaron Szafer, Viktor Szemenyei, Elliot R. Thomsen, Michael Tieu, Amy Torkelson, Jessica Trinh, Herman Tung, Wayne Wakeman, Femke Waleboer, Katelyn Ward, René Wilbers, Grace Williams, Zizhen Yao, Jae-Geun Yoon, Costas Anastassiou, Anton Arkhipov, Pal Barzo, Amy Bernard, Charles Cobbs, Philip C. de Witt Hamer, Richard G. Ellenbogen, Luke Esposito, Manuel Ferreira, Ryder P. Gwinn, Michael J. Hawrylycz, Patrick R. Hof, Sander Idema, Allan R. Jones, C. Dirk Keene, Andrew L. Ko, Gabe J. Murphy, Lydia Ng, Jeffrey G. Ojemann, Anoop P. Patel, John W. Phillips, Daniel L. Silbergeld, Kimberly Smith, Bosiljka Tasic, Rafael Yuste, Idan Segev, Christiaan P. J. de Kock, Huibert D. Mansvelder, Gabor Tamas, Hongkui Zeng, Christof Koch, Ed S. Lein

publication / 2021
Isoform cell-type specificity in the mouse primary motor cortex
Nature
Brain Science
MindScope

A. Sina Booeshaghi, Zizhen Yao, Cindy van Velthoven, Kimberly Smith, Bosiljka Tasic, Hongkui Zeng, Lior Pachter

publication / 2021
Morphological diversity of single neurons in molecularly defined cell types
Nature
Brain Science
MindScope

Hanchuan Peng, Peng Xie, Lijuan Liu, Xiuli Kuang, Yimin Wang, Lei Qu, Hui Gong, Shengdian Jiang, Anan Li, Zongcai Ruan, Liya Ding, Zizhen Yao, Chao Chen, Mengya Chen, Tanya L. Daigle, Rachel Dalley, Zhangcan Ding, Yanjun Duan, Aaron Feiner, Ping He, Chris Hill, Karla E. Hirokawa, Guodong Hong, Lei Huang, Sara Kebede, Hsien-Chi Kuo, Rachael Larsen, Phil Lesnar, Longfei Li, Qi Li, Xiangning Li, Yaoyao Li, Yuanyuan Li, An Liu, Donghuan Lu, Stephanie Mok, Lydia Ng, Thuc Nghi Nguyen, Qiang Ouyang, Jintao Pan, Elise Shen, Yuanyuan Song, Susan M. Sunkin, Bosiljka Tasic, Matthew B. Veldman, Wayne Wakeman, Wan Wan, Peng Wang, Quanxin Wang, Tao Wang, Yaping Wang, Feng Xiong, Wei Xiong, Wenjie Xu, Min Ye, Lulu Yin, Yang Yu, Jia Yuan, Jing Yuan, Zhixi Yun, Shaoqun Zeng, Shichen Zhang, Sujun Zhao, Zijun Zhao, Zhi Zhou, Z. Josh Huang, Luke Esposito, Michael J. Hawrylycz, Staci A. Sorensen, X. William Yang, Yefeng Zheng, Zhongze Gu, Wei Xie, Christof Koch, Qingming Luo, Julie A. Harris, Yun Wang, Hongkui Zeng

publication / 2021
Phenotypic variation of transcriptomic cell types in mouse motor cortex
Nature
Brain Science
MindScope

Federico Scala, Dmitry Kobak, Matteo Bernabucci, Yves Bernaerts, Cathryn René Cadwell, Jesus Ramon Castro, Leonard Hartmanis, Xiaolong Jiang, Sophie Laturnus, Elanine Miranda, Shalaka Mulherkar, Zheng Huan Tan, Zizhen Yao, Hongkui Zeng, Rickard Sandberg, Philipp Berens, Andreas S. Tolias

publication / 2021
QUAREP-LiMi: A community-driven initiative to establish guidelines for quality assessment and reproducibility for instruments and images in light microscopy
Journal of Microscopy
Cell Science

Glyn Nelson, Ulrike Boehm, Steve Bagley, Peter Bajcsy, Johanna Bischof, Claire M. Brown, Aurélien Dauphin, Ian M. Dobbie, John E. Eriksson, Orestis Faklaris, Julia Fernandez-Rodriguez, Alexia Ferrand, Laurent Gelman, Ali Gheisari, Hella Hartmann, Christian Kukat, Alex Laude, Miso Mitkovski, Sebastian Munck, Alison J. North, Tobias M. Rasse, Ute Resch-Genger, Lucas C. Schuetz, Arne Seitz, Caterina Strambio-De-Castillia, Jason R. Swedlow, Ioannis Alexopoulos, Karin Aumayr, Sergiy Avilov, Gert-Jan Bakker, Rodrigo R. Bammann, Andrea Bassi, Hannes Beckert, Sebastian Beer, Yury Belyaev, Jakob Bierwagen, Konstantin A. Birngruber, Manel Bosch, Juergen Breitlow, Lisa A. Cameron, Joe Chalfoun, James J. Chambers, Chieh-Li Chen, Eduardo Conde-Sousa, Alexander D. Corbett, Fabrice P. Cordelieres, Elaine Del Nery, Ralf Dietzel, Frank Eismann, Elnaz Fazeli, Andreas Felscher, Hans Fried, Nathalie Gaudreault, Wah Ing Goh, Thomas Guilbert, Roland Hadleigh, Peter Hemmerich, Gerhard A. Holst, Michelle S. Itano, Claudia B. Jaffe, Helena K. Jambor, Stuart C. Jarvis, Antje Keppler, David Kirchenbuechler, Marcel Kirchner, Norio Kobayashi, Gabriel Krens, Susanne Kunis, Judith Lacoste, Marco Marcello, Gabriel G. Martins, Daniel J. Metcalf, Claire A. Mitchell, Joshua Moore, Tobias Mueller, Michael S. Nelson, Stephen Ogg, Shuichi Onami, Alexandra L. Palmer, Perrine Paul-Gilloteaux, Jaime A. Pimentel, Laure Plantard, Santosh Podder, Elton Rexhepaj, Arnaud Royon, Markku A. Saari, Damien Schapman, Vincent Schoonderwoert, Britta Schroth-Diez, Stanley Schwartz, Michael Shaw, Martin Spitaler, Martin T. Stoeckl, Damir Sudar, Jeremie Teillon, Stefan Terjung, Roland Thuenauer, Christian D. Wilms, Graham D. Wright, Roland Nitschke

publication / 2021
Spatially resolved cell atlas of the mouse primary motor cortex by MERFISH
Nature
Brain Science
MindScope

Meng Zhang, Stephen W. Eichhorn, Brian Zingg, Zizhen Yao, Kaelan Cotter, Hongkui Zeng, Hongwei Dong, Xiaowei Zhuang

publication / 2021
A mechanism for sarcomere breathing: volume change and advective flow within the myofilament lattice
Biophysical Journal
Cell Science

Julie A. Cass, C. David Williams, Thomas C. Irving, Eric Lauga, Sage Malingen, Thomas L. Daniel, Simon N. Sponberg

publication / 2021
Signature morpho-electric, transcriptomic, and dendritic properties of human layer 5 neocortical pyramidal neurons
Neuron
Brain Science
MindScope

Brian E. Kalmbach, Rebecca D. Hodge, Nikolas L. Jorstad, Scott Owen, Rebecca de Frates, Anna Marie Yanny, Rachel Dalley, Matt Mallory, Lucas T. Graybuck, Cristina Radaelli, C. Dirk Keene, Ryder P. Gwinn, Daniel L. Silbergeld, Charles Cobbs, Jeffrey G. Ojemann, Andrew L. Ko, Anoop P. Patel, Richard G. Ellenbogen, Trygve E. Bakken, Tanya L. Daigle, Nick Dee, Brian R. Lee, Medea McGraw, Philip R. Nicovich, Kimberly Smith, Staci A. Sorensen, Bosiljka Tasic, Hongkui Zeng, Christof Koch, Ed S. Lein, Jonathan T. Ting

publication / 2021
Single-cell and single-nucleus RNA-seq uncovers shared and distinct axes of variation in dorsal LGN neurons in mice, non-human primates, and humans
eLife
Brain Science
MindScope

Trygve E. Bakken, Cindy Tj van Velthoven, Vilas Menon, Rebecca D. Hodge, Zizhen Yao, Thuc Nghi Nguyen, Lucas T. Graybuck, Gregory D. Horwitz, Darren Bertagnolli, Jeff Goldy, Anna Marie Yanny, Emma Garren, Sheana Parry, Tamara Casper, Soraya I. Shehata, Eliza R. Barkan, Aaron Szafer, Boaz P. Levi, Nick Dee, Kimberly A. Smith, Susan M. Sunkin, Amy Bernard, John Phillips, Michael J. Hawrylycz, Christof Koch, Gabe J. Murphy, Ed Lein, Hongkui Zeng, Bosiljka Tasic

publication / 2021
Adaptation supports short-term memory in a visual change detection task
PLoS computational biology
Brain Science
MindScope

Brian Hu, Marina E. Garrett, Peter A. Groblewski, Douglas R. Ollerenshaw, Jiaqi Shang, Kate Roll, Sahar Manavi, Christof Koch, Shawn R. Olsen, Stefan Mihalas

publication / 2021
Autoencoder networks extract latent variables and encode these variables in their connectomes
Neural Networks: The Official Journal of the International Neural Network Society
Brain Science
MindScope

Matthew Farrell, Stefano Recanatesi, R. Clay Reid, Stefan Mihalas, Eric Shea-Brown

publication / 2021
Comprehensive in situ mapping of human cortical transcriptomic cell types
Communications Biology
Brain Science
MindScope

Christoffer Mattsson Langseth, Daniel Gyllborg, Jeremy A. Miller, Jennie L. Close, Brian Long, Ed S. Lein, Markus M. Hilscher, Mats Nilsson

publication / 2021
Tetra-gel enables superior accuracy in combined super-resolution imaging and expansion microscopy
Scientific Reports
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Hsuan Lee, Chih-Chieh Yu, Edward S. Boyden, Xiaowei Zhuang, Pallav Kosuri

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