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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
Brain Health accelerator to transform our understanding of brain disorders and develop new treatments
The global collaborative research initiative will initially target Alzheimer’s, Parkinson’s, Huntington’s disease, ALS, and Lewy body dementia

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SciShots: the labyrinthian protein factory of the cell
Graphics software for microscope imagery lights up the endoplasmic reticulum
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SciShots: how the brain plugs leaks
A delicate molecular dance maintains the blood-brain barrier, protecting the brain while allowing transport of necessary resources
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why is the human brain so difficult to understand? we asked four neuroscientists.
Thoughts, memories, sensations - why are we still in the dark about how they work?
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SciShots: gentle imaging for delicate cells
Examining fine cellular details for longer time periods
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SciShots: modeling for the masses
New tool helps scientists see how E. coli finds its center
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Online simulations offer scientists new views inside cells
Simularium Viewer provides interactive visual outputs of computational, biological models
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SciShots: rare kraken cell line released
illuminating structures in Magnumlolligo glacies cells with unprecedented detail
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SciShots: one happy cell (nucleus)
Explorations of the nuclear envelope, the thin membrane surrounding a cell’s chromosomes, reveal unexpected wrinkles
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A day in the (neuroscience) life: OpenScope
Scientists on the OpenScope team help share the Allen Institute’s ‘observatory of the mind’ with the larger scientific community
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A day in the (neuroscience) life: Electron microscopy
Researchers on the EM team are viewing the brain in unprecedented detail
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Allen Institute sets sights on treatments for five brain diseases
The Brain Health Accelerator program aims to harness single-cell transcriptomics and cell-type-specific genetic tools to develop treatments for Alzheimer’s, Huntington’s and Parkinson’s diseases, Lewy body dementia and ALS.
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