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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges

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SciShots: neurons in crisp, clear detail
Electron microscopy reveals the stunning 3D shapes of mouse visual neurons
brain science
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SciShots: a crown of neurons
Brain-wide neuron tracing of cells in the mouse claustrum, a mysterious structure that’s highly connected to the rest of the brain
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SciShots: a neuron’s love connection
A specialized team of neuroscientists at the Allen Institute spend their days painstakingly tracing neurons’ complex branching structures
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A map of all our brains’ blood vessel cells finds new clues to Alzheimer’s disease
Scientists release the first cell-by-cell atlas of the human blood-brain barrier.
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SciShots: a cell’s fate
Synthetic biology is helping scientists understand development
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The Paul G. Allen Frontiers Group announces 23 new Allen Distinguished Investigators
$15.5M in research funding will support cutting-edge projects in mammalian synthetic biology, the neuroscience of under-studied animals, and tiny...
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SciShots: cellular scaffolding
Computer animation techniques light up cells’ inner workings
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SciShots: a star-shaped human brain cell
Scientists catch a glimpse of a rare kind of human astrocyte
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SciShots: an assortment of heart cells
Scientists are capturing the wide visual diversity of human cells
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SciShots: mini-brains
Organoids are miniature versions of organs grown in the lab from stem cells - in many cases, from human stem cells.
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Scientific American: First Atlas of Every Mouse Brain Cell Could Improve Neuro Disease Treatments
Neuroscientists have unveiled their most comprehensive and detailed map of cell types across the entire mouse brain, delivering the latest results of a six-year-long scientific effort in which Seattle’s Allen Institute has played a leading role.
Quanta Magazine: New Cell Atlases Reveal Untold Variety in the Brain and Beyond
(Photo credit: Peter Greenwood for Quanta Magazine.) Recent efforts to map every cell in the human body have researchers floored by unfathomable diversity, with many thousands of subtly different types of cells in the human brain alone.
Seattle Times: Research that brings AI into human cells will soon expand in Seattle
The Seattle Hub for Synthetic Biology, set to open in January, is a result of collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington that aims to build new technologies to record the history of our bodies’ cells.
Yahoo News: Allen Frontiers Group awards $10M to set up research center for neuroimmunology
The neuroimmunology research center will be led by Brian Kim of Mount Sinai and David Artis of Weill Cornell Medicine. They’ll bring together a multidisciplinary team to trace interactions between the nervous system and the immune system that occur at sites distant from the brain.
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