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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges

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Allen Integrated Cell Released Online
Powerful public resource gives researchers a new way to see inside live human cells
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Allen Integrated Cell is a powerful tool for visualizing biology in 3D
Allen Integrated Cell is a new tool that lets anyone visualize cells the way they actually exist in the body.
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Data Stories | Decoding the brain
See how New York high school student Kathleen Esfahany used data from the Allen Brain Observatory to explore the organization and structure of six...
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An ancient pathway that relays visual information in the mammalian brain
Have you ever jumped in fear, and then a split second later realized that a spider (or a spider-shaped shadow) was at the edge of your vision?
brain science
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Allen Cell Methods: RNP transfection for gene editing hiPSCs
To ensure researchers have success working with our cell lines, our Maggie Fuqua demonstrates our RNP transfection protocol for gene editing hiPSCs.
cell science
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Diversity of Cortical Neurons Captured in Comprehensive Computer Models
The Allen Institute for Brain Science has produced the first comprehensive, publicly available database of predictive neuron models, along with their...
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A new approach to studying the human immune system
See how the Allen Institute for Immunology will work to understand the dynamic balancing act of the human immune system, how it senses friend from foe...
immunology
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Meet the Allen Institute for Immunology’s research partners
The Allen Institute for Immunology, a new division of the Allen Institute, launched today.
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The Quest to Unravel The Connectome
Researchers from the Allen Institute for Brain Science are working in collaboration with Baylor College of Medicine, Princeton University and Harvard Medical School.
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Allen Cell Methods: Single cell passaging human iPS cells
To ensure researchers have success working with our human induced pluripotent stem cell lines in their lab, our Amanda Haupt highlights nuanced...
cell science
video
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KIRO Radio: Breakthroughs in Synthetic Biology
(Interview starts 11:35 in) Troy McDiarmid from the Seattle Center for Synthetic Biology describes the innovative research underway to create cellular recorders that will track the full life histories of human cells to better understand disease.
Puget Sound Business Journal: Seattle biotech research hub launches with big goals for growth, scientific advances
The Seattle Hub for Synthetic Biology is developing technology to monitor genomic changes in cells in real time, in turn showing cells' whole histories and the genetic causes of disease.
Inside Precision Medicine: How Single-Cell Omics is Revolutionizing Our View Of Neurobiology
(Photo credit: miakievy / Getty Images) The adult human brain is made up of billions of neurons and glial cells. Understanding the diversity of these cells and their distinctive gene-regulatory mechanisms is crucial for determining how the brain works and, in turn, for developing treatments for neurologic disorders
GeekWire: Inside the new Seattle Hub for Synthetic Biology, which uses DNA to ‘record biology over time’
(Photo credit: Charlotte Schubert) Researchers opened the doors Monday to the new Seattle Hub for Synthetic Biology, a collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington.
Science Friday: 3,000 Types Of Brain Cells Categorized In Massive Brain Cell Atlas
In October 2023, an international group of scientists released an impressively detailed cell atlas of the human brain, published in 21 papers in the journals Science, Science Advances and Science Translational Medicine.
STAT: Allen Institute CEO Rui Costa on mapping the brain and paying early-career scientists decent salaries
Mapping the billions of cells that make up the brain is a task mammoth enough to keep hundreds of researchers across continents busy for years. But it’s just one of several ambitious projects the Allen Institute is helping tackle.
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