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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges
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SciShots: neurons in crisp, clear detail
Electron microscopy reveals the stunning 3D shapes of mouse visual neurons
brain science
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SciShots: a crown of neurons
Brain-wide neuron tracing of cells in the mouse claustrum, a mysterious structure that’s highly connected to the rest of the brain
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SciShots: a neuron’s love connection
A specialized team of neuroscientists at the Allen Institute spend their days painstakingly tracing neurons’ complex branching structures
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A map of all our brains’ blood vessel cells finds new clues to Alzheimer’s disease
Scientists release the first cell-by-cell atlas of the human blood-brain barrier.
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SciShots: a cell’s fate
Synthetic biology is helping scientists understand development
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The Paul G. Allen Frontiers Group announces 23 new Allen Distinguished Investigators
$15.5M in research funding will support cutting-edge projects in mammalian synthetic biology, the neuroscience of under-studied animals, and tiny...
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SciShots: cellular scaffolding
Computer animation techniques light up cells’ inner workings
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SciShots: a star-shaped human brain cell
Scientists catch a glimpse of a rare kind of human astrocyte
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SciShots: an assortment of heart cells
Scientists are capturing the wide visual diversity of human cells
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SciShots: mini-brains
Organoids are miniature versions of organs grown in the lab from stem cells - in many cases, from human stem cells.
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KIRO Radio: Breakthroughs in Synthetic Biology
(Interview starts 11:35 in) Troy McDiarmid from the Seattle Center for Synthetic Biology describes the innovative research underway to create cellular recorders that will track the full life histories of human cells to better understand disease.
Puget Sound Business Journal: Seattle biotech research hub launches with big goals for growth, scientific advances
The Seattle Hub for Synthetic Biology is developing technology to monitor genomic changes in cells in real time, in turn showing cells' whole histories and the genetic causes of disease.
Inside Precision Medicine: How Single-Cell Omics is Revolutionizing Our View Of Neurobiology
(Photo credit: miakievy / Getty Images) The adult human brain is made up of billions of neurons and glial cells. Understanding the diversity of these cells and their distinctive gene-regulatory mechanisms is crucial for determining how the brain works and, in turn, for developing treatments for neurologic disorders
GeekWire: Inside the new Seattle Hub for Synthetic Biology, which uses DNA to ‘record biology over time’
(Photo credit: Charlotte Schubert) Researchers opened the doors Monday to the new Seattle Hub for Synthetic Biology, a collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington.
Science Friday: 3,000 Types Of Brain Cells Categorized In Massive Brain Cell Atlas
In October 2023, an international group of scientists released an impressively detailed cell atlas of the human brain, published in 21 papers in the journals Science, Science Advances and Science Translational Medicine.
STAT: Allen Institute CEO Rui Costa on mapping the brain and paying early-career scientists decent salaries
Mapping the billions of cells that make up the brain is a task mammoth enough to keep hundreds of researchers across continents busy for years. But it’s just one of several ambitious projects the Allen Institute is helping tackle.
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