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Seattle Hub Team

Research for The Seattle Hub for Synthetic Biology (Seattle Hub) is taking place at Allen Institute and University of Washington laboratories.

Meet the researchers teams from the University of Washington and Allen Institute who are supporting research at the Seattle Hub for Synthetic Biology.

Shendure Lab

Trapnell Lab

Pepper Lab

Allen Institute Team

The Shendure Lab

The Shendure Lab is part of the Howard Hughes Medical Institute and the University of Washington’s Department of Genome Sciences. This team is working to develop and apply new technologies and methods for genetics, genomics and molecular biology. Research by the Shendure Lab focuses on next-generation DNA sequencing to measure biological phenomena.

Jay Shendure headshot
(Photo credit: Ron Wurzer/AP Images for HHMI) Jay Shendure, Ph.D., Lead Scientific Director of the Seattle Hub for Synthetic Biology and a professor of genome sciences at the University of Washington School of Medicine.
Sam Regalado headshot

Sam Regalado

University of Washington / Shendure Lab
Junhong Choi headshot

Junhong Choi

University of Washington / Shendure Lab
Riza Daza headshot

Riza Daza

University of Washington / Shendure Lab
Haedong Kim headshot

Haedong Kim

University of Washington / Shendure Lab
Connor Kubo headshot

Connor Kubo

University of Washington / Shendure Lab
Charlie Lee headshot

Charlie Lee

University of Washington / Shendure Lab
Xiaoyi Li headshot

Xiaoyi Li

University of Washington / Shendure Lab
Hanna Liao headshot

Hanna Liao

University of Washington / Shendure Lab
Beth Martin headshot

Beth Martin

University of Washington / Shendure Lab
Troy McDiarmid headshot

Troy McDiarmid

University of Washington / Shendure Lab
Jenny Nathans headshot

Jenny Nathans

University of Washington / Shendure Lab
Chengxiang (CX) Qiu headshot

Chengxiang (CX) Qiu

University of Washington / Shendure Lab
Megan Taylor headshot

Megan Taylor

University of Washington / Shendure Lab
Olga Oseth headshot

Olga Oseth

University of Washington / Shendure Lab
Wei Yang headshot

Wei Yang

University of Washington / Shendure Lab
Qi Yu headshot

Qi Yu

University of Washington / Shendure Lab

The Trapnell Lab

The Trapnell Lab at the University of Washington’s Department of Genome Sciences studies how genomes encode the program of vertebrate development and how that program goes awry in disease. They build new tools, technologies, and software for decoding this program from large-scale single-cell experiments.

Trapnell Headshot
Co-Director, Seattle Hub for Synthetic Biology; Associate Professor of Genome Sciences, University of Washington

The Pepper Lab

In the Pepper Lab, researchers study how cells of the adaptive immune system, called CD4+ T cells and B cells, form immunological memory by visualizing their differentiation, retention and function in both mice and humans. They accomplish this by using novel tetramer-based enrichment strategies to study small populations of antigen specific CD4+ T and B cells in both complex infectious diseases such as malaria as well as during allergic asthma using a house dust mite model. They additionally use transgenic mice with various genetic ablations to interrogate the underlying molecular mechanisms involved in memory cell development and function.

Marion Pepper headshot
Co-Director, Seattle Hub for Synthetic Biology; Professor & Chair of Immunology, University of Washington
Derek Bangs headshot

Derek Bangs

University of Washington / Pepper Lab
Jason Netland headshot

Jason Netland

University of Washington / Pepper Lab
Kurt Pruner headshot

Kurt Pruner

University of Washington / Pepper Lab
Gretchen Harms Pritchard headshot

Gretchen Harms Pritchard

University of Washington / Pepper Lab
Madeleine Weiss headshot

Madeleine Weiss

University of Washington / Pepper Lab
Dan Carr Headshot

Dan Carr

University of Washington / Pepper Lab

Allen Institute Team

The research team at Allen Institute is building cellular recording systems using technologies developed by researchers in the Shendure lab at UW Medicine. These technologies have the potential to record information to the genomes of cells at the scale of the whole organism.

Jesse Gray Headshot
Jesse Gray, Ph.D., Sr. Director, Scientific Operations and Strategy

Science Programs at Allen Institute