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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges

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How your immune system changes over time
Study reveals a type of T cell that vanishes with age and time’s toll on ‘age-resistant’ immune cells
immunology
news

20 Years of Impact | 2023 Annual Report
20 years ago, the Allen Institute began with an idea to do science differently, to take on some of the biggest, hardest problems in biology through...
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annual report

Scientists unveil first complete cellular map of adult mouse brain
High-resolution atlas charts neural neighborhoods for more than 5,300 cell types
brain science
news

How the brain learns to find its next reward: Warm, warmer, hot!
Rewards don’t just reinforce a specific action-they quickly change the whole pattern of how we behave
brain science
news

Seattle Hub for Synthetic Biology launched by Allen Institute, Chan Zuckerberg Initiative, and the University of Washington will turn cells into recording devices to unlock secrets of disease
First-of-its-kind research initiative will develop technologies to reveal how changes in cells and genes over time influence human health and...
synthetic biology
news

Delving into the science of a mystifying optical illusion: visual masking
A new study sheds light on how our brains perceive - or fail to perceive - what we see
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news

The Paul G. Allen Frontiers Group Announces Allen Discovery Center for Neuroimmune interactions at Icahn School of Medicine at Mount Sinai
Multidisciplinary research center to define, map, and understand the health consequences of interactions between the nervous system and the immune...
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news

Society for Neuroscience to honor Michael Stryker, Allen Institute board member, with 2023 Ralph W. Gerard Prize in Neuroscience
The award, which recognizes outstanding career and research achievements, is the highest honor bestowed by the Society for Neuroscience.
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news

Cancer Research Institute awards Ananda Goldrath, Ph.d., with the 2023 Frederick W. Alt Award
The annual honor recognizes outstanding success in academia or industry for research that has had a major impact in the field of immunology.
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news

What makes us human? Detailed cellular maps of the entire human brain reveal clues
You have 3,000+ different kinds of brain cells, and more insights from the largest human brain cell atlases created to date
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news

Hongkui Zeng, Ph.D., Executive Vice President, Director of the Allen Institute for Brain Science, elected to National Academy of Medicine
Election to the Academy is considered one of the highest honors in the fields of health and medicine and recognizes leaders who have demonstrated...
brain science
news
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Puget Sound Business Journal: Seattle biotech research hub launches with big goals for growth, scientific advances
The Seattle Hub for Synthetic Biology is developing technology to monitor genomic changes in cells in real time, in turn showing cells' whole histories and the genetic causes of disease.
Inside Precision Medicine: How Single-Cell Omics is Revolutionizing Our View Of Neurobiology
(Photo credit: miakievy / Getty Images) The adult human brain is made up of billions of neurons and glial cells. Understanding the diversity of these cells and their distinctive gene-regulatory mechanisms is crucial for determining how the brain works and, in turn, for developing treatments for neurologic disorders
GeekWire: Inside the new Seattle Hub for Synthetic Biology, which uses DNA to ‘record biology over time’
(Photo credit: Charlotte Schubert) Researchers opened the doors Monday to the new Seattle Hub for Synthetic Biology, a collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington.
Science Friday: 3,000 Types Of Brain Cells Categorized In Massive Brain Cell Atlas
In October 2023, an international group of scientists released an impressively detailed cell atlas of the human brain, published in 21 papers in the journals Science, Science Advances and Science Translational Medicine.
STAT: Allen Institute CEO Rui Costa on mapping the brain and paying early-career scientists decent salaries
Mapping the billions of cells that make up the brain is a task mammoth enough to keep hundreds of researchers across continents busy for years. But it’s just one of several ambitious projects the Allen Institute is helping tackle.
Scientific American: First Atlas of Every Mouse Brain Cell Could Improve Neuro Disease Treatments
Neuroscientists have unveiled their most comprehensive and detailed map of cell types across the entire mouse brain, delivering the latest results of a six-year-long scientific effort in which Seattle’s Allen Institute has played a leading role.
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