Skip to main content
impact
about
our story
explore our impact
careers and opportunities
join us
open science
sharing science to speed discovery
open science week
celebrating open science
team science
people & teams
discovery is a team effort
allenites
the people who make our work possible
advisors
their input shapes our science
board of directors
they help us fulfill our mission
shanahan foundation fellowship
at the interface of data and neuroscience
next generation leaders
fostering emerging leaders in bioscience
research
overview
our approach
science at the scale of greatest impact
publications
explore our publications
open science
sharing science to speed discovery
science accelerators
brain science
building a blueprint of the brain
cell science
understanding how cells become organs
neural dynamics
revealing the brain’s hidden algorithms
immunology
creating the ultimate immune system reference
synthetic biology
seattle hub for synthetic biology
education
overview
science education
science is for everyone
open science
sharing science speeds discovery
engagement
education resources
real science. real skills.
field trips
experience science where it happens
educator development
empowering educators
news
overview
all news
explore the latest news
podcast
the human stories behind discovery
sign up for our newsletter
stay connected to our science
events
overview
all events
public engagement, workshops, seminars and more
conferences
connect with us
science resources
science resources
allencell.org
allenimmunology.org
allenneuraldynamics.org
brain-bican.org
brain-map.org
microns-explorer.org
impact
back to menu
team science
our story
explore our impact
careers and opportunities
join us
open science
sharing science to speed discovery
open science week
celebrating open science
team science
people & teams
discovery is a team effort
allenites
the people who make our work possible
advisors
their input shapes our science
board of directors
they help us fulfill our mission
shanahan foundation fellowship
at the interface of data and neuroscience
next generation leaders
fostering emerging leaders in bioscience
research
back to menu
overview
our approach
science at the scale of greatest impact
publications
explore our publications
open science
sharing science to speed discovery
science accelerators
brain science
building a blueprint of the brain
cell science
understanding how cells become organs
neural dynamics
revealing the brain’s hidden algorithms
immunology
creating the ultimate immune system reference
synthetic biology
seattle hub for synthetic biology
education
back to menu
overview
science education
science is for everyone
open science
sharing science speeds discovery
engagement
education resources
real science. real skills.
field trips
experience science where it happens
educator development
empowering educators
news
back to menu
overview
all news
explore the latest news
podcast
the human stories behind discovery
newsletter
stay connected to our science
events
back to menu
overview
all events
public engagement, workshops, seminars and more
conferences
connect with us
science resources
back to menu
science resources
allencell.org
allenimmunology.org
allenneuraldynamics.org
brain-bican.org
brain-map.org
microns-explorer.org
search
impact
people

Tanya L. Daigle

Investigator, Assistant

teams /
Allenite

Tanya Daigle joined the Institute in 2013 and currently leads a research team focused on genetic tool development for basic and translational applications. She holds a B.S. degree from U.C. San Diego and a Ph.D. degree in Physiology and Biophysics from the University of Washington in Seattle. She has held research positions at the Salk Institute for Biological Studies, Duke University and the McGovern Institute for Brain Research at MIT. She is a molecular neuroscientist with expertise in the general areas of genetic tool development, neurodegenerative and addiction-related disorders, and human gene therapy.

back to people and teams
featured contributions
featured media
featured stories
featured events
featured publications

featured events

No articles for the category

featured stories

news
Scientists can now target the cells at the center of ALS
For the first time ever, scientists have developed a precise genetic toolkit that can target the exact nerve cells destroyed by ALS-a discovery that...
news
Scientists create next generation of tools in battle against brain disease: The Armamentarium
The findings contained in eight studies could lead to targeted gene therapies for brain disorders
science images
SciShots: Lighting up neurons to combat ALS
Scientists have found a way to selectively target neurons damaged in spinal motor diseases.

featured media

No articles for the category

featured publications

publication / 2025
AAV delivery of full-length SYNGAP1 rescues epileptic and behavioral phenotypes in a mouse model of SYNGAP1-related disorders
Molecular Therapy: The Journal of the American Society of Gene Therapy
publication / 2025
Imaging high-frequency voltage dynamics in multiple neuron classes of behaving mammals
Cell
publication / 2025
Cholinergic neuronal activity promotes diffuse midline glioma growth through muscarinic signaling
Cell
publication / 2025
Enhancer AAVs for targeting spinal motor neurons and descending motor pathways in rodents and macaque
Cell Reports
publication / 2025
Evaluating methods for the prediction of cell-type-specific enhancers in the mammalian cortex
Cell Genomics
publication / 2025
A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types
Cell
publication / 2025
Enhancer AAV toolbox for accessing and perturbing striatal cell types and circuits
Neuron
publication / 2025
VIP-to-SST Cell Circuit Motif Shows Differential Short-Term Plasticity across Sensory Areas of Mouse Cortex
The Journal of Neuroscience: The Official Journal of the Society for Neuroscience
publication / 2024
Publisher Correction: Long-term labeling and imaging of synaptically connected neuronal networks in vivo using double-deletion-mutant rabies viruses
Nature Neuroscience
publication / 2024
Long-term labeling and imaging of synaptically connected neuronal networks in vivo using double-deletion-mutant rabies viruses
Nature Neuroscience
publication / 2023
All-optical recreation of naturalistic neural activity with a multifunctional transgenic reporter mouse
Cell Reports
publication / 2023
A whole-brain monosynaptic input connectome to neuron classes in mouse visual cortex
Nature Neuroscience
publication / 2022
Ventral tegmental area glutamate neurons mediate nonassociative consequences of stress
Molecular Psychiatry
publication / 2022
Intersectional mapping of multi-transmitter neurons and other cell types in the brain
Cell Reports
publication / 2022
Local connectivity and synaptic dynamics in mouse and human neocortex
Science (New York, N.Y.)
publication / 2021
Laminar distribution and arbor density of two functional classes of thalamic inputs to primary visual cortex
Cell Reports
publication / 2021
A multimodal cell census and atlas of the mammalian primary motor cortex
Nature
publication / 2021
Morphological diversity of single neurons in molecularly defined cell types
Nature
publication / 2021
Comparative cellular analysis of motor cortex in human, marmoset and mouse
Nature
publication / 2021
Signature morpho-electric, transcriptomic, and dendritic properties of human layer 5 neocortical pyramidal neurons
Neuron
publication / 2021
Enhancer viruses for combinatorial cell-subclass-specific labeling
Neuron
publication / 2021
Alternating sources of perisomatic inhibition during behavior
Neuron
publication / 2020
Integrated Morphoelectric and Transcriptomic Classification of Cortical GABAergic Cells
Cell
publication / 2020
Brainwide Genetic Sparse Cell Labeling to Illuminate the Morphology of Neurons and Glia with Cre-Dependent MORF Mice
Neuron
publication / 2020
RecV recombinase system for in vivo targeted optogenomic modifications of single cells or cell populations
Nature Methods
publication / 2019
Visual Cortex Gains Independence from Peripheral Drive before Eye Opening
Neuron
publication / 2019
Classification of electrophysiological and morphological neuron types in the mouse visual cortex
Nature Neuroscience
publication / 2019
In Vivo Submillisecond Two-Photon Optogenetics with Temporally Focused Patterned Light
The Journal of Neuroscience: The Official Journal of the Society for Neuroscience
publication / 2018
Shared and distinct transcriptomic cell types across neocortical areas
Nature
publication / 2018
A Suite of Transgenic Driver and Reporter Mouse Lines with Enhanced Brain-Cell-Type Targeting and Functionality
Cell
publication / 2017
A robot for high yield electrophysiology and morphology of single neurons in vivo
Nature Communications
publication / 2014
Acute brain slice methods for adult and aging animals: application of targeted patch clamp analysis and optogenetics
Methods in Molecular Biology (Clifton, N.J.)
publication
Enhancer AAVs for targeting spinal motor neurons and descending motor pathways in rodents and macaque
we acceleratedevelopcatalyzeimpact

science done differently. shared openly.

explore our accelerators

brain science

Mapping every cell, connection, and circuit in the brain—openly shared with the world.

cell science

Decoding how cells become tissues, then programming that knowledge into powerful new research tools.

neural dynamics

Revealing the brain's hidden algorithms that transform neural activity into real-world behavior.

immunology

Creating the deepest open reference for the healthy human immune system ever built.

synthetic biology

Engineering cells to record their own histories, transforming how we understand disease over time.

research

Big questions, open answers, and science built to be shared.

education

Inspiring the next generation of scientists through open science resources.

impact

Our science is empowering researchers and advancing health worldwide.
advancing science through open, collaborative research
Get the allen institute newsletter
Stay informed on the latest breakthroughs in neuroscience, bioscience, and AI-driven research.
allen institute
impactpeople & teamscareers & opportunitiesalumnihistory & founder
science resources
allencell.orgallenimmunology.orgallenneuraldynamics.orgbrain-bican.orgbrain-map.orgmicrons-explorer.org
research
brain sciencecell scienceneural dynamicsimmunologysynthetic biologypublications
education
science educationfield tripsprofessional developmenteducation resources
quick links
newseventsopen sciencepodcastscience resourceshuman brain donationvisit uscontact
follow us/

allen institute, 615 Westlake Ave North, Seattle, WA 98109 +12065487055

© 0000 allen institute. all rights reserved.
privacy policyterms of usecitation policyemployee portalpolicy & compliancecookie settings