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The complex processing of the brain is intimately tied to the structural and functional connections that individual neurons and networks of neurons make. For many decades anatomical studies have guided us as to which brain regions and local populations likely make synaptic contact. I am interested in understanding the functional interactions served by these physical connections as this is how the brain communicates. With the multi-patch team I will record from many neurons simultaneously to uncover the transmission of neural signals between them. By utilizing transgenic mouse lines we can describe the connections of specific neuron types in order to form a rich view of specific connectivity in the brain and ultimately how this leads to behavior.