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Claire Gustafson

Assistant Investigator

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Allenite

Claire is an Assistant Investigator in Experimental Immunology at the Allen Institute for Immunology. Prior to joining the Allen Institute, Claire was an Instructor in Immunology and Rheumatology at Stanford University. Her research focused on understanding the mechanistic underpinnings of immune aging in humans utilizing high-dimensional techniques in conjunction with the development of novel model systems to accelerate translational human immunology research. For her postdoctoral training, Claire investigated molecular regulators of T cell homeostasis and responses to aging, infection and vaccination, under the mentorship of Dr. Jorg Goronzy at Stanford University. She also was involved in multiple projects assessing whether certain disease states and/or treatments accelerate immune aging.

Claire earned her Ph.D. in Immunology from University of Colorado, Anschutz Medical Campus, with a certificate in Clinical and Translational Science, where she studied mucosal antibody development during human infancy. She received a B.S. in Molecular, Cellular and Development Biology from University of Washington.

research focus

Claire’s underlying scientific focus is understanding normal, healthy immune development, function and variation over the course of a lifespan, as a basis for determining the cause of any immunological perturbations; from infection to autoimmunity to cancer.

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How age affects vaccine responses and how to make them better
Age-related shifts in T cells weaken vaccine response in older adults, but new findings pave the way for next generation of vaccines.
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Allen Institute for Immunology unveils landmark Human Immune Health Atlas
Comprehensive dataset maps the landscape of healthy immune cells across the human lifespan
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How your immune system changes over time
Study reveals a type of T cell that vanishes with age and time’s toll on ‘age-resistant’ immune cells

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publication / 2025
CryoSCAPE: Scalable immune profiling using cryopreserved whole blood for multi-omic single cell and functional assays
Journal of Translational Medicine
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