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team science
our story
explore our impact
careers and opportunities
join us
open science
sharing science to speed discovery
open science week
celebrating open science
team science
people & teams
discovery is a team effort
allenites
the people who make our work possible
advisors
their input shapes our science
board of directors
they help us fulfill our mission
shanahan foundation fellowship
at the interface of data and neuroscience
next generation leaders
fostering emerging leaders in bioscience
research
back to menu
overview
our approach
science at the scale of greatest impact
publications
explore our publications
open science
sharing science to speed discovery
science accelerators
brain science
building a blueprint of the brain
cell science
understanding how cells become organs
neural dynamics
revealing the brain’s hidden algorithms
immunology
creating the ultimate immune system reference
synthetic biology
seattle hub for synthetic biology
education
back to menu
overview
science education
science is for everyone
open science
sharing science speeds discovery
engagement
education resources
real science. real skills.
field trips
experience science where it happens
educator development
empowering educators
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all news
explore the latest news
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the human stories behind discovery
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brain-bican.org
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featured events
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featured stories
news
Mapping the brain to improve lives
A collaborative effort between UW and the Allen Institute is creating a first-of-its-kind brain atlas, paving the way for breakthroughs in brain...
news
So you want to donate your brain to science
Monte Strohl donated his brain to research after his death, hoping to fuel science and help others with neurodegenerative conditions.
video
Where does Alzheimer's begin?
Pinpointing the cellular roots of Alzheimer's disease to find new targets for treatments and therapies.
featured media
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featured publications
publication
/
2025
Accelerating biomedical discoveries in brain health through transformative neuropathology of aging and neurodegeneration
Neuron
publication
/
2024
Integrated multimodal cell atlas of Alzheimer's disease
Nature Neuroscience
publication
/
2024
SEA-AD is a multimodal cellular atlas and resource for Alzheimer's disease
Nature Aging
publication
/
2024
Mapping human tissues with highly multiplexed RNA in situ hybridization
Nature Communications
publication
/
2024
Hierarchical Bayesian inference to model continuous phenotypical progression in Alzheimer's Disease
bioRxiv
publication
/
2023
Transcriptomic diversity of cell types across the adult human brain
Science (New York, N.Y.)
publication
/
2023
Single-cell DNA methylation and 3D genome architecture in the human brain
Science (New York, N.Y.)
publication
/
2023
Signature morphoelectric properties of diverse GABAergic interneurons in the human neocortex
Science (New York, N.Y.)
publication
/
2023
Comparative transcriptomics reveals human-specific cortical features
Science (New York, N.Y.)
publication
/
2023
A comparative atlas of single-cell chromatin accessibility in the human brain
Science (New York, N.Y.)
publication
/
2023
Interindividual variation in human cortical cell type abundance and expression
Science (New York, N.Y.)
publication
/
2023
Transcriptomic cytoarchitecture reveals principles of human neocortex organization
Science (New York, N.Y.)
publication
/
2023
Morphoelectric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex
Science (New York, N.Y.)
publication
/
2023
Ferroptosis of Microglia in Aging Human White Matter Injury
Annals of Neurology
publication
/
2023
Target cell-specific synaptic dynamics of excitatory to inhibitory neuron connections in supragranular layers of human neocortex
eLife
publication
/
2022
Local connectivity and synaptic dynamics in mouse and human neocortex
Science (New York, N.Y.)
publication
/
2021
A multimodal cell census and atlas of the mammalian primary motor cortex
Nature
publication
/
2021
Human neocortical expansion involves glutamatergic neuron diversification
Nature
publication
/
2021
Comparative cellular analysis of motor cortex in human, marmoset and mouse
Nature
publication
/
2021
Signature morpho-electric, transcriptomic, and dendritic properties of human layer 5 neocortical pyramidal neurons
Neuron
publication
/
2021
Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex
Cell Reports
publication
/
2021
The Delayed Neuropathological Consequences of Traumatic Brain Injury in a Community-Based Sample
Frontiers in Neurology
publication
/
2019
Conserved cell types with divergent features in human versus mouse cortex
Nature
publication
/
2018
h-Channels Contribute to Divergent Intrinsic Membrane Properties of Supragranular Pyramidal Neurons in Human versus Mouse Cerebral Cortex
Neuron
publication
/
2018
A robust ex vivo experimental platform for molecular-genetic dissection of adult human neocortical cell types and circuits
Scientific Reports
publication
/
2018
An anatomic transcriptional atlas of human glioblastoma
Science (New York, N.Y.)
publication
/
2017
Neuropathological and transcriptomic characteristics of the aged brain
eLife
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brain science
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neural dynamics
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immunology
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