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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
Brain Health accelerator to transform our understanding of brain disorders and develop new treatments
The global collaborative research initiative will initially target Alzheimer’s, Parkinson’s, Huntington’s disease, ALS, and Lewy body dementia

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scientists fix genetic defect in mice tied to brain disorders that include autism and epilepsy
Gene therapy successfully reduced epileptic activity, hyperactivity and risk-taking behaviors tied to SYNGAP1-related disorders
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news

scientists create ChatGPT-like AI model for neuroscience to build detailed mouse brain map
Scientists create ChatGPT-like AI model for neuroscience to build one of the most detailed mouse brain maps to date.
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study reveals rheumatoid arthritis begins long before symptoms, opening door to prevention
The seven-year study reveals early-warning signs that could help doctors catch the disease before it starts, potentially saving patients years of pain and disability.
immunology
news

Simularium: accelerating discovery by animating insight
Simularium is an innovative online tool designed by the Allen Institute’s Cell Science team that visualizes 4D simulations (animations) of complex...
cell science
video

scientists use Open Ephys GUI to study how psychedelics affect the brain
Software co-created by the Allen Institute is helping scientists better understand psilocybin, which could lead to new treatments for neuropsychiatric disorders like depression
neural dynamics
news
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news

scientists shoot lasers into brain cells to uncover how illusions work
Supported by the Allen Institute's OpenScope program, the findings could help us better understand neuropsychiatric disorders like schizophrenia and...
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news

Allen Institute cells blast off into outer space
Researchers from Cedars-Sinai are using Allen Institute cell lines to grow organoids in space, which could help design better drugs for disease
cell science
news
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multimedia

learning how to learn with brains, data and optimization
A Shanahan Fellow’s experience to uncover how the brain multitasks and adapts to the world around it.
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Billionaire Paul Allen Donates $100 Million To Fund A 'Manhattan Project' For Human Disease
Paul Allen, the Microsoft cofounder turned billionaire philanthropist, will donate $100 million to create a research center tasked with investigating the inner workings of human cells. The ultimate goal is to deepen our understanding of how diseases emerge and how they can be treated and prevented.
Biologists Get $100 Million From Billionaire Paul Allen To Investigate Cells
With a gift of $100 million from billionaire philanthropist Paul G. Allen, scientists will embark on an effort to understand how cells work and how they malfunction in disease. Leaders of this new endeavor announced the launch of the Seattle-based Allen Institute for Cell Science today at the annual meeting of the American Society for Cell Biology in Philadelphia.
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