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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules

Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges
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scientists complete first drafts of developing mammalian brain cell atlases
New research reveals how early brains form and the critical periods that could help diagnose and treat brain disease.
brain science
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Allen Institute announces 2025 Next Generation Leaders
The program continues to expand beyond neuroscience. This year, researchers bring critical expertise in theory, immunology, and cell biology
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making connections
How Yiliu Wang's found her place in neuroscience during the Shanahan Fellowship.
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how age affects vaccine responses and how to make them better
Age-related shifts in T cells weaken vaccine response in older adults, but new findings pave the way for next generation of vaccines.
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Susan Kaech, Ph.D., named next leader of Allen Institute’s Immunology accelerator
Leader in immunology to advance the Institute’s next frontier in understanding the immune system’s role across health and disease
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Karel Svoboda and Jay Shendure elected to National Academy of Medicine
The honor recognizes leaders who have demonstrated outstanding achievement and made lasting contributions to the advancement of the medical sciences,...
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from Datasets to AI Data Dreams with Refik Anadol
Named to the TIME100 AI list, artist Refik Anadol explores how data becomes art and AI reshapes perception
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scientists fix genetic defect in mice tied to brain disorders that include autism and epilepsy
Gene therapy successfully reduced epileptic activity, hyperactivity and risk-taking behaviors tied to SYNGAP1-related disorders
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scientists create ChatGPT-like AI model for neuroscience to build detailed mouse brain map
Scientists create ChatGPT-like AI model for neuroscience to build one of the most detailed mouse brain maps to date.
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study reveals rheumatoid arthritis begins long before symptoms, opening door to prevention
The seven-year study reveals early-warning signs that could help doctors catch the disease before it starts, potentially saving patients years of pain and disability.
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Simularium: accelerating discovery by animating insight
Simularium is an innovative online tool designed by the Allen Institute’s Cell Science team that visualizes 4D simulations (animations) of complex...
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scientists use Open Ephys GUI to study how psychedelics affect the brain
Software co-created by the Allen Institute is helping scientists better understand psilocybin, which could lead to new treatments for neuropsychiatric disorders like depression
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media / GeekWire
They’re alive! Allen Institute harvests data from bits of living human brain tissue
GeekWire - Zapping brain cells from living human tissue? It sounds like a creepy Halloween tale.
media / Forbes
Paul Allen Just Made His Biggest Step Yet To Map The Human Brain
Forbes - When the Allen Institute for Brain Science launched its Cell Types Database just over two years ago, its goal was to help create a comprehensive map of the human brain
media / Allen Institute
Allen Institute shares first open database of live human brain cells
Brain samples from neurosurgery patients reveal uniqueness and complexity of the human brain
media / Allen Institute
Allen Institute for Brain Science awarded ~$100 million to lead global collaborations that will build comprehensive atlases of brain cell types
National Institutes of Health funding expands work to identify and catalog the building blocks of the brain, and creates global center for data sharing
media / GeekWire
Brain scientist Christof Koch maps out a path to merge humans and machines
GeekWire - It may sound like a zombie movie, but Seattle’s Allen Institute for Brain Science is studying fresh human brain tissue to see up close how our neurons work.
media / Science News for Students
Cool Jobs: Puzzling over proteins to study life and death
Ru Gunawardane's team is studying how proteins help our cells divide, move and communicate. These scientists also are making their maps of living cells and other information available to researchers elsewhere around the world.
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media / Wired UK
Not so grey matter! Brain scans are transformed into beautiful and sprawling works of neon art
Wired - Beautiful images of your brain reveal to scientists how you function
media / Nature
The trickiest family tree in biology
Nature - Scientists are striving for a deeper view of development, from embryo to adult, cell-by-cell.
media / Nature
Chinese rocket failure, Fukushima trial and discarded fish
Nature - The Paul G. Allen Frontiers Group said on 5 July that it will establish two US biological research centers.
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