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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges

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Karel Svoboda and Jay Shendure elected to National Academy of Medicine
The honor recognizes leaders who have demonstrated outstanding achievement and made lasting contributions to the advancement of the medical sciences,...
synthetic biology
neural dynamics
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from Datasets to AI Data Dreams with Refik Anadol
Named to the TIME100 AI list, artist Refik Anadol explores how data becomes art and AI reshapes perception
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scientists fix genetic defect in mice tied to brain disorders that include autism and epilepsy
Gene therapy successfully reduced epileptic activity, hyperactivity and risk-taking behaviors tied to SYNGAP1-related disorders
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scientists create ChatGPT-like AI model for neuroscience to build detailed mouse brain map
Scientists create ChatGPT-like AI model for neuroscience to build one of the most detailed mouse brain maps to date.
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study reveals rheumatoid arthritis begins long before symptoms, opening door to prevention
The seven-year study reveals early-warning signs that could help doctors catch the disease before it starts, potentially saving patients years of pain and disability.
immunology
news

Simularium: accelerating discovery by animating insight
Simularium is an innovative online tool designed by the Allen Institute’s Cell Science team that visualizes 4D simulations (animations) of complex...
cell science
video

scientists use Open Ephys GUI to study how psychedelics affect the brain
Software co-created by the Allen Institute is helping scientists better understand psilocybin, which could lead to new treatments for neuropsychiatric disorders like depression
neural dynamics
news
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scientists shoot lasers into brain cells to uncover how illusions work
Supported by the Allen Institute's OpenScope program, the findings could help us better understand neuropsychiatric disorders like schizophrenia and...
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Allen Institute cells blast off into outer space
Researchers from Cedars-Sinai are using Allen Institute cell lines to grow organoids in space, which could help design better drugs for disease
cell science
news
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multimedia
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Seattle researchers lead ambitious project to map the human brain
We could be on the cusp of breakthrough treatments for brain diseases, from Alzheimer's Disease to depression and ADHD. Local scientists from the Allen Institute for Brain Science are spearheading a five-year project to map the human brain.
NIH launches the next stage of its ‘human genome project’ for the brain
The National Institutes of Health on Thursday announced more than $600 million in fresh funding for an expansive and ongoing push to unravel the mysteries of the human brain, bankrolling efforts to create a detailed map of the whole brain, and devise new ways to target therapeutics and other molecules to specific brain cell populations.
Data Trove Released by Seattle Alzheimer’s Disease Brain Cell Atlas
Neuroscientists at the Allen Institute for Brain Science and their collaborators have released their first research data set on Alzheimer’s disease, in which they categorized cell types based on gene activity. The team hope this approach could ultimately identify new targets for better therapies.
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