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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges

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Allen Institute Education Lab to offer innovative training and workshops to current and future scientists
The custom-built learning space immerses students, educators, and scientists in authentic learning experiences
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Scientists create next generation of tools in battle against brain disease: The Armamentarium
The findings contained in eight studies could lead to targeted gene therapies for brain disorders
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Allen Institute launches new initiative to transform our understanding of how human cells build tissues and organs
cell science
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Landmark experiment sheds new light on the origins of consciousness
Findings suggest it may be about sensory processing and perception, with possible implications for diagnosing and treating comas or vegetative states.
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Jessica Oparebea is hoping to use science to heal and restore lives
Driven by a passion for neuroscience and optics, and inspired by the TReND-CaMinA workshop, Jessica hopes to develop breakthroughs in brain-machine interfaces
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Scientists complete largest wiring diagram and functional map of the brain to date
The MICrONS Project is considered the most complicated neuroscience experiment ever attempted
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Revealing the largest wiring diagram and functional map of the brain through MICrONS
Scientists have created the largest wiring diagram and functional map of an animal brain
brain science
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Attempting the impossible: A 20-year journey to learn the language of the brain
In what is considered the most complicated neuroscience experiment ever attempted, scientists from the Allen Institute and global collaborators have...
brain science
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Explore the connections of the brain - MICrONS neuroscience data insights
This video showcases neuroscience data insights from the MICrONS project
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Breakthrough Dravet Syndrome gene therapy in mice brings new hope to families
In a groundbreaking advancement scientists have developed a new gene replacement therapy in mice that could lead to more effective treatments in...
brain science
multimedia
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Seattle scientists launch $95 million AI biology effort
The Allen Institute, University of Washington, and Fred Hutch Cancer Center are launching a $95 million effort to use AI to design biology that doesn’t exist in nature. Called AI BioDesign and led scientifically by Nobel laureate David Baker and genome scientist Jay Shendure, the initiative will use AI models to propose new DNA sequences and biological molecules.

AI learns nature’s code: Allen Institute, UW and Fred Hutch launch $95M open science initiative
Three of Seattle’s top scientific institutions are launching a nearly $95 million research initiative that will generate data and train AI models to design proteins and genes that don’t exist in nature — sharing the results freely to help others develop new medicines and materials.

‘It’s going to come quicker than we think’: Parkinson’s advocate shares hope for treatment as Allen Institute launches AI-powered initiative
The institute has launched the Brain Health Accelerator, an international collaboration involving about 30 research organizations that will use artificial intelligence, human brain tissue and advanced cellular mapping to better understand diseases including Parkinson’s, Alzheimer’s disease, ALS, Huntington’s disease and Lewy body dementia.
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