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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges

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Karel Svoboda and Jay Shendure elected to National Academy of Medicine
The honor recognizes leaders who have demonstrated outstanding achievement and made lasting contributions to the advancement of the medical sciences,...
synthetic biology
neural dynamics
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from Datasets to AI Data Dreams with Refik Anadol
Named to the TIME100 AI list, artist Refik Anadol explores how data becomes art and AI reshapes perception
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scientists fix genetic defect in mice tied to brain disorders that include autism and epilepsy
Gene therapy successfully reduced epileptic activity, hyperactivity and risk-taking behaviors tied to SYNGAP1-related disorders
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scientists create ChatGPT-like AI model for neuroscience to build detailed mouse brain map
Scientists create ChatGPT-like AI model for neuroscience to build one of the most detailed mouse brain maps to date.
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study reveals rheumatoid arthritis begins long before symptoms, opening door to prevention
The seven-year study reveals early-warning signs that could help doctors catch the disease before it starts, potentially saving patients years of pain and disability.
immunology
news

Simularium: accelerating discovery by animating insight
Simularium is an innovative online tool designed by the Allen Institute’s Cell Science team that visualizes 4D simulations (animations) of complex...
cell science
video

scientists use Open Ephys GUI to study how psychedelics affect the brain
Software co-created by the Allen Institute is helping scientists better understand psilocybin, which could lead to new treatments for neuropsychiatric disorders like depression
neural dynamics
news
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scientists shoot lasers into brain cells to uncover how illusions work
Supported by the Allen Institute's OpenScope program, the findings could help us better understand neuropsychiatric disorders like schizophrenia and...
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Allen Institute cells blast off into outer space
Researchers from Cedars-Sinai are using Allen Institute cell lines to grow organoids in space, which could help design better drugs for disease
cell science
news
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multimedia
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Seattle scientists launch $95 million AI biology effort
The Allen Institute, University of Washington, and Fred Hutch Cancer Center are launching a $95 million effort to use AI to design biology that doesn’t exist in nature. Called AI BioDesign and led scientifically by Nobel laureate David Baker and genome scientist Jay Shendure, the initiative will use AI models to propose new DNA sequences and biological molecules.

AI learns nature’s code: Allen Institute, UW and Fred Hutch launch $95M open science initiative
Three of Seattle’s top scientific institutions are launching a nearly $95 million research initiative that will generate data and train AI models to design proteins and genes that don’t exist in nature — sharing the results freely to help others develop new medicines and materials.

‘It’s going to come quicker than we think’: Parkinson’s advocate shares hope for treatment as Allen Institute launches AI-powered initiative
The institute has launched the Brain Health Accelerator, an international collaboration involving about 30 research organizations that will use artificial intelligence, human brain tissue and advanced cellular mapping to better understand diseases including Parkinson’s, Alzheimer’s disease, ALS, Huntington’s disease and Lewy body dementia.
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