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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges

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Allen Institute Education Lab to offer innovative training and workshops to current and future scientists
The custom-built learning space immerses students, educators, and scientists in authentic learning experiences
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Scientists create next generation of tools in battle against brain disease: The Armamentarium
The findings contained in eight studies could lead to targeted gene therapies for brain disorders
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Allen Institute launches new initiative to transform our understanding of how human cells build tissues and organs
cell science
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Landmark experiment sheds new light on the origins of consciousness
Findings suggest it may be about sensory processing and perception, with possible implications for diagnosing and treating comas or vegetative states.
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Jessica Oparebea is hoping to use science to heal and restore lives
Driven by a passion for neuroscience and optics, and inspired by the TReND-CaMinA workshop, Jessica hopes to develop breakthroughs in brain-machine interfaces
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Scientists complete largest wiring diagram and functional map of the brain to date
The MICrONS Project is considered the most complicated neuroscience experiment ever attempted
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Revealing the largest wiring diagram and functional map of the brain through MICrONS
Scientists have created the largest wiring diagram and functional map of an animal brain
brain science
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Attempting the impossible: A 20-year journey to learn the language of the brain
In what is considered the most complicated neuroscience experiment ever attempted, scientists from the Allen Institute and global collaborators have...
brain science
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Explore the connections of the brain - MICrONS neuroscience data insights
This video showcases neuroscience data insights from the MICrONS project
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Breakthrough Dravet Syndrome gene therapy in mice brings new hope to families
In a groundbreaking advancement scientists have developed a new gene replacement therapy in mice that could lead to more effective treatments in...
brain science
multimedia
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Puget Sound Business Journal: Seattle biotech research hub launches with big goals for growth, scientific advances
The Seattle Hub for Synthetic Biology is developing technology to monitor genomic changes in cells in real time, in turn showing cells' whole histories and the genetic causes of disease.
Inside Precision Medicine: How Single-Cell Omics is Revolutionizing Our View Of Neurobiology
(Photo credit: miakievy / Getty Images) The adult human brain is made up of billions of neurons and glial cells. Understanding the diversity of these cells and their distinctive gene-regulatory mechanisms is crucial for determining how the brain works and, in turn, for developing treatments for neurologic disorders
GeekWire: Inside the new Seattle Hub for Synthetic Biology, which uses DNA to ‘record biology over time’
(Photo credit: Charlotte Schubert) Researchers opened the doors Monday to the new Seattle Hub for Synthetic Biology, a collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington.
Science Friday: 3,000 Types Of Brain Cells Categorized In Massive Brain Cell Atlas
In October 2023, an international group of scientists released an impressively detailed cell atlas of the human brain, published in 21 papers in the journals Science, Science Advances and Science Translational Medicine.
STAT: Allen Institute CEO Rui Costa on mapping the brain and paying early-career scientists decent salaries
Mapping the billions of cells that make up the brain is a task mammoth enough to keep hundreds of researchers across continents busy for years. But it’s just one of several ambitious projects the Allen Institute is helping tackle.
Scientific American: First Atlas of Every Mouse Brain Cell Could Improve Neuro Disease Treatments
Neuroscientists have unveiled their most comprehensive and detailed map of cell types across the entire mouse brain, delivering the latest results of a six-year-long scientific effort in which Seattle’s Allen Institute has played a leading role.
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