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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges

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SciShots: how the brain plugs leaks
A delicate molecular dance maintains the blood-brain barrier, protecting the brain while allowing transport of necessary resources
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why is the human brain so difficult to understand? we asked four neuroscientists.
Thoughts, memories, sensations - why are we still in the dark about how they work?
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SciShots: gentle imaging for delicate cells
Examining fine cellular details for longer time periods
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SciShots: modeling for the masses
New tool helps scientists see how E. coli finds its center
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Online simulations offer scientists new views inside cells
Simularium Viewer provides interactive visual outputs of computational, biological models
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SciShots: rare kraken cell line released
illuminating structures in Magnumlolligo glacies cells with unprecedented detail
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SciShots: one happy cell (nucleus)
Explorations of the nuclear envelope, the thin membrane surrounding a cell’s chromosomes, reveal unexpected wrinkles
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A day in the (neuroscience) life: OpenScope
Scientists on the OpenScope team help share the Allen Institute’s ‘observatory of the mind’ with the larger scientific community
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A day in the (neuroscience) life: Electron microscopy
Researchers on the EM team are viewing the brain in unprecedented detail
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Science in Sixty | Luke Campagnola
When Luke Campagnola isn't investigating the complexities of mammalian brain circuitry, he's spending time with family and practicing parkour.
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Puget Sound Business Journal: Seattle biotech research hub launches with big goals for growth, scientific advances
The Seattle Hub for Synthetic Biology is developing technology to monitor genomic changes in cells in real time, in turn showing cells' whole histories and the genetic causes of disease.
Inside Precision Medicine: How Single-Cell Omics is Revolutionizing Our View Of Neurobiology
(Photo credit: miakievy / Getty Images) The adult human brain is made up of billions of neurons and glial cells. Understanding the diversity of these cells and their distinctive gene-regulatory mechanisms is crucial for determining how the brain works and, in turn, for developing treatments for neurologic disorders
GeekWire: Inside the new Seattle Hub for Synthetic Biology, which uses DNA to ‘record biology over time’
(Photo credit: Charlotte Schubert) Researchers opened the doors Monday to the new Seattle Hub for Synthetic Biology, a collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington.
Science Friday: 3,000 Types Of Brain Cells Categorized In Massive Brain Cell Atlas
In October 2023, an international group of scientists released an impressively detailed cell atlas of the human brain, published in 21 papers in the journals Science, Science Advances and Science Translational Medicine.
STAT: Allen Institute CEO Rui Costa on mapping the brain and paying early-career scientists decent salaries
Mapping the billions of cells that make up the brain is a task mammoth enough to keep hundreds of researchers across continents busy for years. But it’s just one of several ambitious projects the Allen Institute is helping tackle.
Scientific American: First Atlas of Every Mouse Brain Cell Could Improve Neuro Disease Treatments
Neuroscientists have unveiled their most comprehensive and detailed map of cell types across the entire mouse brain, delivering the latest results of a six-year-long scientific effort in which Seattle’s Allen Institute has played a leading role.
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