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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules

Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges
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Out of Balance | Alyssa’s life with Crohn’s disease
Ever since Alyssa Clements can remember, she’s wanted to be a doctor. Her father is a chiropractor in south New Jersey, and his business partner was...
immunology
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New Cell Registry enables exploration of multiple brain cell type datasets
The Allen Institute for Brain Science, a division of the Allen Institute, has debuted a new data exploration tool for brain cell type data.
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How do living creatures take shape?
Think of the shape of life. Living creatures have forms ranging from a tiny rod-shaped bacterium, to a wrinkled, tusked behemoth of an elephant, to a...
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Q&A: A former experimental psychologist with a passion for data governance
Scientists everywhere are struggling with data. Paul Meijer, Ph.D., Director of Software Development at the newly launched Allen Institute for...
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Gene drives get a precision upgrade
Gene drives, a method to “drive” a new gene through a population in a way that bypasses the natural order of inheritance, were first developed...
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A new technique to make beating human heart cells glow
Allen Institute for Cell Science researchers have developed a new technique that will enable better understanding of human heart muscle cells.
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Data Stories | Addiction & the visual system
Researcher Randy Ellis studies computational neuroscience and addiction. Ellis uses the Allen Brain Observatory dataset in his work to find new ways...
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How immune cells detect different threat levels from salmonella
Your immune system has a tough job.
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5 unsolved mysteries about the brain
Can we understand our own brains? We have a long way to go, neuroscientists say.
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Out of Balance | Tom Bumol’s life after lymphoma
What happens when an immunologist gets a life-threatening, immune-related disease? In Bumol’s case, he doubles down on his research.
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2 million-cell experiment traces how a mammal grows, cell by single cell
The very early days of growth, long before we are born, are a time of incredible development.
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New VR game lets you learn about cells by tossing them
The app teaches users the stages of cell division through interactions with 3D models of human cells
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media / GeekWire
GeekWire: Scientists unveil new wiring diagram tracing millions of connections in a bit of brain tissue
Researchers say they’ve accomplished the impossible: mapping the cells in a cubic millimeter of brain tissue and tracing their activity.
media / USA Today
USA Today: A mouse watched YouTube. Then scientists mapped a tiny piece of its brain.
Scientists have achieved a feat once believed impossible, constructing the largest functional map of a mouse brain to date.
media / The Guardian
The Guardian: US scientists create most comprehensive circuit diagram of mammalian brain
The 3D map of a cubic millimeter of mouse brain reveals half a billion synapses and 5.4km of neuronal wiring.
media / Scientific American
Scientific American: Biggest Brain Map Ever Shows Mouse Neurons in Stunning Detail
Researchers have created the largest and most detailed wiring diagram of a mammalian brain to date―a neuroscience first.
media / Reuters
Reuters: Scientists produce painstaking wiring diagram of a mouse's brain
Neuroscientists have produced the largest wiring diagram and functional map of a mammalian brain, offering insight into how the human brain works.
media / The Transmitter
The Transmitter: Split gene therapy delivers promise in mice modeling Dravet syndrome
A potential new gene therapy for Dravet syndrome increases survival and prevents seizures in mice, a new study shows.
media / Associated Press
Associated Press: Scientists map part of a mouse’s brain that’s so complex it looks like a galaxy
Thanks to a mouse watching clips from “The Matrix,” scientists have created the largest functional map of a brain to date.
media / New York Times
New York Times: An Advance in Brain Research That Was Once Considered Impossible
Scientists achieved “a milestone” by charting the activity and structure of 200,000 cells in a mouse brain and their 523 million connections.
media / The Transmitter
The Transmitter: Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain
A cubic millimeter of brain tissue reveals in stunning detail the role of inhibitory interneurons in brain structure and function.
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