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Data gathered with Neuropixels, tiny silicon probes capable of recording electrical activity from hundreds of neurons at a time.

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Allen Institute for Brain Science Database Release Nearly Doubles Mouse Brain Cell Data

Jun 21, 2018

The Allen Institute for Brain Science today announced the release of new data, tools to analyze those data and a new web-based 3D viewer to explore...

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Glowing Betz cells, a huge type of specialized motor neuron found in primates but not in rodents, in the macaque monkey brain. Scientists at the Allen Institute label these neurons using a modified virus that is capable of delivering fluorescent cargo to a specific class of neuron in the brain.

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New fluorescently tagged cell lines available, including first ‘silent’ tagged line

Jun 19, 2018

The Allen Cell Collection now contains five new fluorescently tagged stem cell lines, including the first cells in the collection with a tag specific...

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The Visual Guide to Human Cells lets users rotate, zoom in and out, and highlight different structures inside a 3D model of a human stem cell.

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Picture a cell: New 3D visual guide can help

Jun 18, 2018

Last month, Allen Institute for Cell Science researchers debuted the Visual Guide to Human Cells, a 3D interactive tool that aims to help scientists...

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Allen Institute researchers have found that there’s more to our cells than genes alone reveal. Here, an image of human heart muscle cells, or cardiomyocytes, grown from human stem cells shows the variability in organization among structures inside the cells.

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New technique captures view of 10,000 genes’ activity in the moment

Jun 7, 2018

The technique, which the researchers dubbed seqFISH, detects a very transient form of RNA, the go-between molecule that bridges the gap between a gene...

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From left: Brian Kalmbach, senior scientist; Nick Dee, senior manager for tissue processing; and Windy Ho, research assistant, prepare a piece of brain

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Human brain tissue stays alive in the lab for three days

Jun 4, 2018

For much of his career, neuroscientist Jonathan Ting, Ph.D., studied rodent brains. But because his research relies on live neurons, those studies...

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The Allen Cell & Structure Segmenter is a Python-based open source toolkit developed for 3D segmentation of intracellular structures in fluorescence microscope images.

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The brain cells that drive schizophrenia

May 24, 2018

A new study led by researchers at the Karolinska Institutet in Solna, Sweden, in collaboration with scientists from the Allen Institute for Brain...

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Image of human skull taken via MRI

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Brain Tumor Atlas Published in the Journal Science

May 11, 2018

Researchers around the world use publicly available Ivy Glioblastoma Atlas Project to investigate aggressive brain cancer

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May 10, 2018

The American Heart Association and Paul G. Allen Frontiers Group will fund $43 million worth of research bringing together scientists focusing on...

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Keene points out brain slices from an 83-year old man who had died of Alzheimer's disease and donated his brain to research. The slices are preserved so that scientists can study how brain structures have changed in the disease. Photo by Erik Dinnel / Allen Institute

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May 10, 2018

The Paul G. Allen Frontiers Group and the American Heart Association/American Stroke Association announced today a new research initiative to support...

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Image showing the average location of 17 different internal structures inside a human cell. A new study from the Allen Institute for Cell Science builds a framework for quantifying the organization of cellular structures.

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Allen Integrated Cell Released Online

May 9, 2018

Powerful public resource gives researchers a new way to see inside live human cells

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Science Programs at Allen Institute