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Palak Genge an Allen Institute researcher

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New study aims to answer pressing COVID-19 question: Why do some die while others don’t even know they are sick?

Dec 21, 2020

Seattle-area research organizations team up for a deep dive into patients’ immune responses to the novel coronavirus; results could contribute to...

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A morphological reconstruction of a VIP interneuron courtesy for the Allen Cell Types team over a gradient calcium image of VIP interneurons from the Allen Brain Observatory team.

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These visual neurons catch what we might miss

Dec 16, 2020

When mice see faint objects approaching head on, certain neurons kick into gear — possibly to warn them

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The Allen Institute headquarters located in Seattle, Washington.

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Allen Institute for Cell Science announces leadership changes

Dec 11, 2020

Ruwanthi (Ru) Gunawardane, Ph.D., has been named Executive Director.

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Allen Institute announces 2020 Next Generation Leaders

Nov 18, 2020

Six early-career neuroscientists will participate in unique advisory council for the Institute

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A technique that captures information about a neuron's 3D shape, electrical properties, and its genes is giving scientists a new way to look at cell types in the mouse brain and the relationship between them — described in this illustration as a 'family tree' of neurons. Illustration by Benedicte Rossi.

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The mammalian brain is built from many kinds of neurons. A new study reveals a holistic way to look at them.

Nov 12, 2020

Using a technique that simultaneously captures different kinds of features from each cell, researchers lay groundwork for a “family tree” of the...

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Image of an astrocyte

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Oct 21, 2020

Astrocytes, once thought of as inert ‘brain glue,’ may turn out to be key players in Huntington’s and other neurodegenerative diseases

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The CRISPR interference technique allows new explorations of human cells. Here, Allen Distinguished Investigator Martin Kampmann, Ph.D., and his colleagues used the method to reduce levels of a dementia-associated protein known as progranulin, shown in green on the left, in human neurons by dialing down the progranulin gene in the cells on the right. (Image adapted from Tian et al (2019) Neuron 104:239)

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New cell line lets researchers use CRISPR to reversibly switch off genes

Oct 20, 2020

‘CRISPR interference’ technique enables study of basic cell biology and disease in human stem cells

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2 scientists win Nobel chemistry prize for gene-editing tool

Oct 20, 2020

Allen Distinguished Investigator Jennifer A. Doudna and her colleague Emmanuelle Charpentier won for developing CRISPR-cas9, a very simple technique...

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Research teams at the Allen Institute are part of newly launched efforts to understand the cell nucleus. Here, an image from the Allen Institute for Cell Science shows models of nuclei from human stem cells, highlighting two different structures inside each nucleus: nuclear speckles (yellow) and nucleoli (cyan and magenta).

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Projects launch to map the nucleus, the information center of our cells

Oct 15, 2020

Teams from two divisions of the Allen Institute, the Allen Institute for Cell Science and the Allen Institute for Brain Science, are participating in...

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The Paul G. Allen Frontiers Group Announces New Allen Distinguished Investigators

Oct 8, 2020

Collaborative projects funded by the awards will address important questions about neurodegenerative disease, nucleus biology, and protein turnover

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