Solving the mysteries of bioscience
Foundational Science Fuels Breakthroughs
Inspiring Next-Generation Scientists
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Since 2003, the Allen Institute has pioneered an approach to science that unlocks discoveries and advances our understanding of human health.
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In the News
Apr 15, 2025
Using a speck of mouse brain matter the size of a grain of sand, scientists have created the first precise, three-dimensional map of a mammal’s...
Apr 14, 2025
In 1979 the Nobel prize-winning biologist Francis Crick marvelled at the human brain’s capacity to explore itself. Yet, even as he celebrated its...
Researchers say they’ve accomplished a feat that was said to be impossible 46 years ago: mapping the cells in a cubic millimeter of brain tissue and...
Scientists have achieved a feat once believed impossible, constructing the largest functional map of a brain to date, which they believe could...
The 3D map of a cubic millimetre of mouse brain reveals half a billion synapses and 5.4km of neuronal wiring.
Researchers have created the largest and most detailed wiring diagram of a mammalian brain to date, by mapping cells in a cubic millimetre of a...
Apr 11, 2025
Neuroscientists have produced the largest wiring diagram and functional map of a mammalian brain to date using tissue from a part of a mouse's...
A potential new gene therapy for Dravet syndrome increases survival and prevents seizures, according to initial tests in mice, a new study shows. The...
Thanks to a mouse watching clips from “The Matrix,” scientists have created the largest functional map of a brain to date – a diagram of the...
Scientists achieved “a milestone” by charting the activity and structure of 200,000 cells in a mouse brain and their 523 million connections.
Mar 20, 2025
Scientists from the Allen Institute and Seattle Children’s Research Institute have announced a breakthrough in the development of gene replacement...
Scientists at the Allen Institute have made a major breakthrough in research for people living with Dravet Syndrome, which is a rare and debilitating...
Scientists at the Allen Institute for Brain Science are working on a promising gene therapy that could offer a life-saving treatment for children...
Mar 6, 2025
The Seattle Hub for Synthetic Biology is receiving a $10 million grant to support the training of new scientists and the launch of biotech startups...
Mar 3, 2025
These networks align with different assemblages of cells, a finding that could reveal how cellular diversity influences brain function, according to a...
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Author lists on papers have ballooned, and it’s getting hard to discern contribution.
Founder Paul G. Allen believed in answering big, fundamental questions in biology (Big Science). The approach to tackling these questions is rooted in Team Science: where experts across multiple fields leverage unique talents in a coordinated, collaborative way to produce massive amounts of high-quality data. The data, tools, and resources created are freely available (Open Science) to the entire scientific community. Big, Team and Open Science–as practiced by the Allen Institute–accelerates progress, amplifies impact and benefits all.