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Since 2003, the Allen Institute has pioneered an approach to science that unlocks discoveries and advances our understanding of human health.

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All of these images show a subset of more than 1,000 of the 120,000 brain cells (neuron + glia) reconstructed in the MICRONS project. Each reconstructed neuron is a different random color. In some of the images, a subset of the neurons have been rendered as glowing in different ways to represent the fact that this dataset includes functional recordings from a subset of neurons.

In the News

CNN: Scientists reveal advance in brain research once thought impossible

Apr 15, 2025

Using a speck of mouse brain matter the size of a grain of sand, scientists have created the first precise, three-dimensional map of a mammal’s...

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In the News

The Times of London: New map of brain hailed as watershed for neuroscience

Apr 14, 2025

In 1979 the Nobel prize-winning biologist Francis Crick marvelled at the human brain’s capacity to explore itself. Yet, even as he celebrated its...

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Microns image from the Neural Coding team at the Allen Institute for Brain Science. This image shows colorful renderings of neurons and their synaptic connections.

In the News

GeekWire: Scientists unveil new wiring diagram tracing millions of connections in a bit of brain tissue

Apr 14, 2025

Researchers say they’ve accomplished a feat that was said to be impossible 46 years ago: mapping the cells in a cubic millimeter of brain tissue and...

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All of these images show a subset of more than 1,000 of the 120,000 brain cells (neuron + glia) reconstructed in the MICRONS project. Each reconstructed neuron is a different random color. In some of the images, a subset of the neurons have been rendered as glowing in different ways to represent the fact that this dataset includes functional recordings from a subset of neurons.

In the News

USA Today: A mouse watched YouTube. Then scientists mapped a tiny piece of its brain.

Apr 14, 2025

Scientists have achieved a feat once believed impossible, constructing the largest functional map of a brain to date, which they believe could...

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Scientists at Allen Institute examining neuronal reconstruction data

In the News

The Guardian: US scientists create most comprehensive circuit diagram of mammalian brain

Apr 14, 2025

The 3D map of a cubic millimetre of mouse brain reveals half a billion synapses and 5.4km of neuronal wiring.

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In the News

Scientific American: Biggest Brain Map Ever Shows Mouse Neurons in Stunning Detail

Apr 14, 2025

Researchers have created the largest and most detailed wiring diagram of a mammalian brain to date, by mapping cells in a cubic millimetre of a...

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In the News

Reuters: Scientists produce painstaking wiring diagram of a mouse’s brain

Apr 11, 2025

Neuroscientists have produced the largest wiring diagram and functional map of a mammalian brain to date using tissue from a part of a mouse's...

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In the News

The Transmitter: Split gene therapy delivers promise in mice modeling Dravet syndrome

Apr 11, 2025

A potential new gene therapy for Dravet syndrome increases survival and prevents seizures, according to initial tests in mice, a new study shows. The...

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Scientists on the Neural Coding team at the Allen Institute

In the News

Associated Press: Scientists map part of a mouse’s brain that’s so complex it looks like a galaxy

Apr 11, 2025

Thanks to a mouse watching clips from “The Matrix,” scientists have created the largest functional map of a brain to date – a diagram of the...

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All of these images show a subset of more than 1,000 of the 120,000 brain cells (neuron + glia) reconstructed in the MICRONS project. Each reconstructed neuron is a different random color. In some of the images, a subset of the neurons have been rendered as glowing in different ways to represent the fact that this dataset includes functional recordings from a subset of neurons.

In the News

New York Times: An Advance in Brain Research That Was Once Considered Impossible

Apr 11, 2025

Scientists achieved “a milestone” by charting the activity and structure of 200,000 cells in a mouse brain and their 523 million connections.

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John Mich in the lab at the Allen Institute

In the News

Gene Therapy Tested in Mice Offers New Hope for People with Dravet Syndrome

Mar 20, 2025

Scientists from the Allen Institute and Seattle Children’s Research Institute have announced a breakthrough in the development of gene replacement...

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Boaz Levi in the lab

In the News

Groundbreaking gene therapy research in Washington could lead to treat children living with severe epilepsy

Mar 20, 2025

Scientists at the Allen Institute have made a major breakthrough in research for people living with Dravet Syndrome, which is a rare and debilitating...

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Boaz Levi and John Mich in the lab of the Allen Institute in Seattle, WA

In the News

Breakthrough gene therapy in Seattle offers hope for children with epilepsy

Mar 20, 2025

Scientists at the Allen Institute for Brain Science are working on a promising gene therapy that could offer a life-saving treatment for children...

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Seattle Hub Geekwire photo

In the News

GeekWire: Seattle Hub for Synthetic Biology lands $10M to support ‘DNA Typewriter’ technology

Mar 6, 2025

The Seattle Hub for Synthetic Biology is receiving a $10 million grant to support the training of new scientists and the launch of biotech startups...

GeekWire
Visualization of the human brain.

In the News

Cell ‘fingerprints’ identify distinct cortical networks

Mar 3, 2025

These networks align with different assemblages of cells, a finding that could reveal how cellular diversity influences brain function, according to a...

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A visualization of a large-scale model of a mouse visual cortex brain circuit, built at the Allen Institute and containing 230,000 neuron building-block models, recently published in the journal Neuron. Image courtesy of Sergey Gratiy, Ph.D.

In the News

News

The last two-author neuroscience paper?

Mar 3, 2025

Author lists on papers have ballooned, and it’s getting hard to discern contribution.

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Founder Paul G. Allen believed in answering big, fundamental questions in biology (Big Science). The approach to tackling these questions is rooted in Team Science: where experts across multiple fields leverage unique talents in a coordinated, collaborative way to produce massive amounts of high-quality data. The data, tools, and resources created are freely available (Open Science) to the entire scientific community. Big, Team and Open Science–as practiced by the Allen Institute–accelerates progress, amplifies impact and benefits all.

Science Programs at Allen Institute