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Peter Skene

Sr. Director, High Resolution Immunology

teams /
Allenite

Pete Skene joined the Allen Institute for Immunology in 2019 as the Director of High Resolution Translational Immunology. Prior to joining, Pete was at the Fred Hutchinson Research Center and Nanostring Technologies here in Seattle where he worked to invent new sequencing based technologies. These include CUT&RUN which has enabled our understanding of genomic regulatory mechanisms across many biological systems and is the foundation for many related platforms.

Here at the Allen Institute, Pete’s team focuses on development, automation, and application of high resolution technologies to further understand and perturb immune cell states across health and disease. This includes the invention of novel assays such as TEA-seq and innovative spatial biology approaches. In collaboration with other teams, these foundational technologies and resulting datasets are leading to ground breaking insights into the human immune system, and provide landmark datasets for the broader research community.

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SciShots: Nervous and immune systems team up to take on parasites
Pain-sensing neurons in the intestine give marching orders to the immune system to kick off an attack against parasites
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CryoSCAPE: Allen Institute scientists develop ‘suspended animation’ technique for blood draws that will aid research for underserved populations
A new approach that keeps blood cells alive in deep freeze promises to expand reach of cutting-edge single-cell technologies to underserved...
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How your immune system changes over time
Study reveals a type of T cell that vanishes with age and time’s toll on ‘age-resistant’ immune cells

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publication / 2025
Provide proactive reproducible analysis transparency with every publication
Royal Society Open Science
publication / 2021
Simultaneous trimodal single-cell measurement of transcripts, epitopes, and chromatin accessibility using TEA-seq
eLife
publication
Optimized workflow for human PBMC multiomic immunosurveillance studies
publication
Multimodal analysis for human ex vivo studies shows extensive molecular changes from delays in blood processing
publication
BarWare: efficient software tools for barcoded single-cell genomics
publication
A comprehensive platform for analyzing longitudinal multi-omics data
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