Glial cells are a critical component of the brain. Long viewed as supporting cells to neurons, their roles in maintaining homeostasis, fostering intercellular communications and reacting to injury and disease, are subjects of intense investigation. I am interested in what functions OPCs(oligodendrocyte precursor cells) play in the brain, and how they become myelinating oligodendrocytes and interact with microglia. Volume electron microscopy has provided large amounts of data that will enable insight into the cell biology of these enigmatic cells.ExpertiseElectron microscopyCell BiologyNeuroanatomyData analysisNeural CodingEM Connectomics