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Cindy van Velthoven

Cindy van Velthoven, Ph.D.

Associate Investigator

Bio:

Cindy van Velthoven joined the Allen Institute as part of a large effort to define cell types in the developing and adult mouse brain. Here she develops and applies computational tools to identify cell types in various mouse brain regions and characterize changes in gene regulation associated with development or experimental perturbations.
Prior to joining the Allen Institute, she completed her postdoctoral training in the lab of Tom Rando at Stanford University where she studied post-transcriptional mechanisms involved in regulating stem cell quiescence. She used various transcriptional and translational profiling techniques to probe the earliest activation changes in quiescent stem cells in vivo. Cindy received her Ph.D. in neuroscience from Utrecht University, The Netherlands, where she examined the use of stem cells to repair the neonatal brain after ischemic injury. Prior to that Cindy earned a M.S. in pathobiology from Radboud University Nijmegen, the Netherlands.

Research Focus:

My main interest is in understanding how a cell navigates the cell fate determination process. During development, cells must proliferate, differentiate, and signal to each other to ensure correct organization within structures. Gene expression, regulated by transcription factor networks, aides in coordinating growth, shape, and function of cells. Using their epigenomic and transcriptional profiles, we can distinguish cell types and increase our understanding of cell fate determination.