Brock Roberts, Ph.D.

Scientist III

Cell Science

Bio:

Brock leads the genome engineering team at the Allen Institute for Cell Science, and has been involved in the production of human induced pluripotent stem cell lines for the larger community as part of the Allen Cell Collection since the Institute's inception. Brock joined the Institute soon after completing his Ph.D. in Molecular and Cell Biology at UC Berkeley, where he performed some genome engineering experiments in mouse embryonic stem cells with exogenous nucleases in order to mechanistically dissect the role of the Hedgehog signaling pathway in patterning of the spinal cord.

Research Focus:

Brock is interested in genome engineering and cellular signaling pathways functioning in early human development, and how those two interests merge. The mechanistic determinants of cellular diversity produced by developmental events and changes in the cell's state are primary interest.

Brock Roberts, Ph.D.

Publications

Integrated intracellular organization and its variations in human iPS cells

Fluorescent Gene Tagging of Transcriptionally Silent Genes in hiPSCs

Systematic gene tagging using CRISPR/Cas9 in human stem cells to illuminate cell organization

Endogenous Protein Tagging in Human Induced Pluripotent Stem Cells Using CRISPR/Cas9

Science Programs at Allen Institute