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From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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Mind trip: How psilocybin changes the brain

New research may help improve psychedelic therapy for neuropsychiatric disorders
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Data Stories | How a weight loss drug acts on the brain
Scientists at a pharmaceutical company want to know how the drug they developed for weight management affects the brain. Allen Institute resources are...
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A computational challenge to help developmental biology
Q&A with the scientists and organizers behind a new competition to use machine learning to reconstruct an entire animal’s developmental lineage
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Three collaborative studies launch on ‘OpenScope,’ a shared observatory for neuroscience
2019 projects will tackle Alzheimer’s disease, motion detection, and how the brain processes contextual information
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Allen Cell Methods: Cryopreservation of clonal human iPS cell lines in 96-well plates
To ensure researchers have success working with human induced pluripotent stem cell lines from the Allen Cell Catalog, Amanda Haupt, a research...
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How the gut keeps time - and keeps us healthy
New study identifies brain-intestine circadian signals that could underlie health problems related to night shift work and poor sleep
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Highest-Resolution Human Brain 'Parts List' To Date Lays Road Map to Better Treatments for Neurological and Psychiatric Disorders
Crucial differences discovered in human and mice brain cells could explain why many drugs that work in the lab don’t work in us
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This is what it’s like to donate your brain to science
Casey Schorr underwent invasive surgery to quell the epileptic seizures that were taking over his life. Now, a small piece of his brain tissue is...
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Virtual reality is helping neuroscientists better understand the brain
When Elise Shen goes to work, her morning starts much like that of anyone else with a desk job. She greets her coworkers. She fetches a cup of coffee....
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Simulations of life - in health and disease
Across many areas of biology, researchers are turning to virtual simulations to help ask and answer important questions.
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Machine learning toolkit lets biologists navigate their way through a 3D cell
In the world of computer vision, engineers need to build software that can recognize parts of an image or 3D visual field. Think, for example, a...
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These neurons are tied to one of multiple sclerosis’ most dramatic effects: Brain shrinkage
Multiple sclerosis begins with a maddening back and forth.
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Advancing Leading Edge Cancer Research in a $4.5 Million Collaboration
LLS, The Mark Foundation for Cancer Research and The Paul G. Allen Frontiers Group Join Forces to Advance Leading Edge Cancer Research
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media / Puget Sound Business Journal
Allen Institute a key research partner in Obama's BRAIN initiative
Puget Sound Business Journal - The Allen Institute for Brain Science has earmarked $60 million annually toward research that will support President Barack Obama’s new initiative for brain research.
media / Forbes
Inside Paul Allen's Quest To Reverse Engineer The Brain
Forbes - Paul Allen, the 59-year-old Microsoft cofounder who has plowed $500 million into the Allen Institute for Brain Science, a medical Manhattan Project that he hopes will dwarf his contribution as one of the founding fathers of software.
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media / BBC
Human brain gene map shows striking similarities
BBC - Human brains follow the same basic molecular pattern despite different individual personalities, a 3D map of where our genes are expressed suggests.
media / The Guardian
Scientists create atlas of human brain
The Guardian - Map reveals the activity of genes across the entire brain to help shed light on neurological and psychiatric conditions
media / NBC News
New atlas may help solve mysteries of the human brain
NBC News - The genetic differences between normal and abnormal human brains may be determined one day from a "brain atlas" scientists are refining.
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media / The Lancet
Journey into the circuits of the mind
The Lancet - The Allen Institute for Brain Science is embarking on a new mission: to elucidate the inner workings of the brain.
media / Xconomy
Paul Allen’s Big Bet to ‘Uncover the Essence of What Makes Us Human’
Xconomy - Yesterday, Paul Allen made clear that he wants to be the guy who helped spark new understanding of the human brain.
media / Wall Street Journal
Project to Explore Human Perception
The Wall Street Journal - The Allen Institute for Brain Science announced Wednesday that Microsoft Corp. co-founder Paul G. Allen had donated $300 million to launch an effort to map the brain's basic circuitry of perception.
media / New York Times
Paul Allen Gives Millions for Brain Research
The New York Times - Paul G. Allen, a co-founder of Microsoft, announced on Wednesday that he would commit $300 million over the next 10 years to turn the Allen Institute for Brain Science, a nonprofit organization he established to build a database of neural information, into a center for basic neuroscience investigation.
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