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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules

Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges
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Allen Cell Methods: Cryopreservation of clonal human iPS cell lines in 96-well plates
To ensure researchers have success working with human induced pluripotent stem cell lines from the Allen Cell Catalog, Amanda Haupt, a research...
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How the gut keeps time - and keeps us healthy
New study identifies brain-intestine circadian signals that could underlie health problems related to night shift work and poor sleep
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Highest-Resolution Human Brain 'Parts List' To Date Lays Road Map to Better Treatments for Neurological and Psychiatric Disorders
Crucial differences discovered in human and mice brain cells could explain why many drugs that work in the lab don’t work in us
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This is what it’s like to donate your brain to science
Casey Schorr underwent invasive surgery to quell the epileptic seizures that were taking over his life. Now, a small piece of his brain tissue is...
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Virtual reality is helping neuroscientists better understand the brain
When Elise Shen goes to work, her morning starts much like that of anyone else with a desk job. She greets her coworkers. She fetches a cup of coffee....
brain science
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Simulations of life - in health and disease
Across many areas of biology, researchers are turning to virtual simulations to help ask and answer important questions.
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Machine learning toolkit lets biologists navigate their way through a 3D cell
In the world of computer vision, engineers need to build software that can recognize parts of an image or 3D visual field. Think, for example, a...
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These neurons are tied to one of multiple sclerosis’ most dramatic effects: Brain shrinkage
Multiple sclerosis begins with a maddening back and forth.
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Advancing Leading Edge Cancer Research in a $4.5 Million Collaboration
LLS, The Mark Foundation for Cancer Research and The Paul G. Allen Frontiers Group Join Forces to Advance Leading Edge Cancer Research
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Sorting neurons by their shape and activity to understand the elements making up the brain
To understand our brains, scientists need to know their components. This theme underlies a growing effort in neuroscience to define the different building blocks of the brain — its cells.
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A model for how the brain stays in sync
In the brain, connections are key. A mouse brain contains around a billion synapses, or physical connections between neurons, and our own brains house approximately 100 trillion.
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Allen Institute for Cell Science Debuts First Comprehensive View of Human Cell Division
The data-driven model sheds new light on mitosis, a critical process for human cells and a pivotal driver of cancer
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The Paul G. Allen Frontiers Group Names ICM's Bassem Hassan a New Allen Distinguished Investigator
The Paul G. Allen Frontiers Group today named Bassem Hassan, Ph.D., at the Institut du Cerveau et de la Moelle épinière (ICM) in Paris an Allen Distinguished Investigator (ADI) with an award for research at the frontier of neural circuit development and behavior, titled “How developmental noise in neural circuit development determines the unique behavior of individuals.”
media / Allen Institute
The Paul G. Allen Frontiers Group Announces Allen Discovery Center at Tufts University
The Paul G. Allen Frontiers Group announced today the creation of an Allen Discovery Center at Tufts University for Reading and Writing the Morphogenetic Code, to be led by Professor of Biology Michael Levin, Ph.D. The Allen Discovery Center at Tufts will focus on learning to read, interpret and manipulate the biological code that determines how complex anatomical structures are created and regulated, with potentially enormous impact for regenerative medicine and bioengineering.
media / Washington Post
Philanthropist Paul Allen announces $100 million gift to expand ‘frontiers of bioscience’
The Washington Post - Billionaire philanthropist Paul Allen has announced a $100 million commitment over 10 years to fund scientific endeavors at the “frontiers of bioscience."
media / TechCrunch
Microsoft co-founder Paul Allen pledges $100 million toward cutting-edge biotech research
TechCrunch - Investor, entrepreneur, billionaire and Bill Gates’ other half in the founding of Microsoft Paul Allen has announced a $100 million investment in the Paul G. Allen Frontiers Group.
media / STAT News
Billionaire Paul Allen bets $100 million on risky scientific research
STAT - The Frontiers Group, launched Wednesday, will start by bankrolling two Allen Discovery Centers; each will receive about $30 million over eight years.
media / GeekWire
Paul Allen launches $100M Frontiers Group program for ‘out-of-the-box’ bioscience
GeeWire - Seattle billionaire Paul Allen added another venture to his philanthropic portfolio today with the creation of the Paul G. Allen Frontiers Group.
media / Forbes
Paul Allen's Plan To Pour $100M Into 'Out-Of-The-Box' Biotech Research
Forbes - Philanthropist and Microsoft co-founder Paul Allen has spent millions of dollars on research designed to unravel the intricacies of the human brain.
media / Bloomberg
Billionaire Allen Gives $100 Million for Bioscience Research
Bloomberg - Paul Allen, the billionaire owner of the Seattle Seahawks football team, will give away $100 million to fund risky life-science research.
media / Spectrum News
Sequencing approach bares large variety of brain cell types
Spectrum - Gene expression profiles for more than 1,600 cells from a small section of the mouse brain have revealed 49 different cell types, nearly twice as many as had previously been identified in this brain area.
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