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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules

Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges
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Allen Cell Methods: Cryopreservation of clonal human iPS cell lines in 96-well plates
To ensure researchers have success working with human induced pluripotent stem cell lines from the Allen Cell Catalog, Amanda Haupt, a research...
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How the gut keeps time - and keeps us healthy
New study identifies brain-intestine circadian signals that could underlie health problems related to night shift work and poor sleep
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Highest-Resolution Human Brain 'Parts List' To Date Lays Road Map to Better Treatments for Neurological and Psychiatric Disorders
Crucial differences discovered in human and mice brain cells could explain why many drugs that work in the lab don’t work in us
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This is what it’s like to donate your brain to science
Casey Schorr underwent invasive surgery to quell the epileptic seizures that were taking over his life. Now, a small piece of his brain tissue is...
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Virtual reality is helping neuroscientists better understand the brain
When Elise Shen goes to work, her morning starts much like that of anyone else with a desk job. She greets her coworkers. She fetches a cup of coffee....
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Simulations of life - in health and disease
Across many areas of biology, researchers are turning to virtual simulations to help ask and answer important questions.
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Machine learning toolkit lets biologists navigate their way through a 3D cell
In the world of computer vision, engineers need to build software that can recognize parts of an image or 3D visual field. Think, for example, a...
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These neurons are tied to one of multiple sclerosis’ most dramatic effects: Brain shrinkage
Multiple sclerosis begins with a maddening back and forth.
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Advancing Leading Edge Cancer Research in a $4.5 Million Collaboration
LLS, The Mark Foundation for Cancer Research and The Paul G. Allen Frontiers Group Join Forces to Advance Leading Edge Cancer Research
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Sorting neurons by their shape and activity to understand the elements making up the brain
To understand our brains, scientists need to know their components. This theme underlies a growing effort in neuroscience to define the different building blocks of the brain — its cells.
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A model for how the brain stays in sync
In the brain, connections are key. A mouse brain contains around a billion synapses, or physical connections between neurons, and our own brains house approximately 100 trillion.
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Allen Institute for Cell Science Debuts First Comprehensive View of Human Cell Division
The data-driven model sheds new light on mitosis, a critical process for human cells and a pivotal driver of cancer
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media / GeekWire
They’re alive! Allen Institute harvests data from bits of living human brain tissue
GeekWire - Zapping brain cells from living human tissue? It sounds like a creepy Halloween tale.
media / Forbes
Paul Allen Just Made His Biggest Step Yet To Map The Human Brain
Forbes - When the Allen Institute for Brain Science launched its Cell Types Database just over two years ago, its goal was to help create a comprehensive map of the human brain
media / Allen Institute
Allen Institute shares first open database of live human brain cells
Brain samples from neurosurgery patients reveal uniqueness and complexity of the human brain
media / Allen Institute
Allen Institute for Brain Science awarded ~$100 million to lead global collaborations that will build comprehensive atlases of brain cell types
National Institutes of Health funding expands work to identify and catalog the building blocks of the brain, and creates global center for data sharing
media / GeekWire
Brain scientist Christof Koch maps out a path to merge humans and machines
GeekWire - It may sound like a zombie movie, but Seattle’s Allen Institute for Brain Science is studying fresh human brain tissue to see up close how our neurons work.
media / Science News for Students
Cool Jobs: Puzzling over proteins to study life and death
Ru Gunawardane's team is studying how proteins help our cells divide, move and communicate. These scientists also are making their maps of living cells and other information available to researchers elsewhere around the world.
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media / Wired UK
Not so grey matter! Brain scans are transformed into beautiful and sprawling works of neon art
Wired - Beautiful images of your brain reveal to scientists how you function
media / Nature
The trickiest family tree in biology
Nature - Scientists are striving for a deeper view of development, from embryo to adult, cell-by-cell.
media / Nature
Chinese rocket failure, Fukushima trial and discarded fish
Nature - The Paul G. Allen Frontiers Group said on 5 July that it will establish two US biological research centers.
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