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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
Brain Health accelerator to transform our understanding of brain disorders and develop new treatments
The global collaborative research initiative will initially target Alzheimer’s, Parkinson’s, Huntington’s disease, ALS, and Lewy body dementia

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New insights about evolution of human brain region that controls voluntary movement, including rare, large neurons vulnerable in ALS
Is our brain like that of a mouse or a monkey? New study aims to find our cellular similarities - and key differences
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An ultra detailed map of the brain region that controls movement, from mice to monkeys to humans
Hundreds of neuroscientists built a ‘parts list’ of the motor cortex, laying groundwork to map the whole brain and better understand brain disease...
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These rare human neurons generate electrical signals in two different cellular parts
With brain tissue samples donated by surgery patients come detailed descriptions of certain rare types of human cells - including new findings about...
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Q&A with the Allen Institute for Immunology’s first employee
Ernie Coffey started his career in science with a bang. It was 1997 and he landed a job at one of the institutes participating in the sequencing of...
immunology
news

Sped-up evolution may have molded the human brain by slowing neuron growth
Quickly evolving stretches of DNA unique to humans are important for brain development, a new study finds
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Brain scientists unveil wiring diagram containing 200,000 cells and nearly half billion connections in tiny piece of a mouse's brain
Detailed map captures 3D shapes of neurons and their synapses in stunning detail and is open to community for neuroscience and machine learning...
brain science
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To understand human cells, scientists look beyond genes
Deep dive into detailed images of human heart cells uncovers a disconnect between gene expression and cell structure
cell science
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Science in Sixty | Shannon Reynolds
Figuring out how to transport live brain tissue from the operating room to the lab is challenging to say the least. In our latest Science in Sixty,...
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Study maps all the types of neurons across two major structures of the mouse brain
Cell-type parts list of the mouse neocortex and the hippocampal formation yields new information about how the mammalian brain evolved and develops
brain science
news
Science in Sixty | Brian Lee
Brian Lee, Ph.D., Senior Scientist at the Allen Institute for Brain Science, shares his journey from rebellious teen to crisis counselor to neuroscientist.
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The Paul G. Allen Frontiers Group Announces Allen Discovery Center at Boston Children's Hospital and Harvard Medical School
The Paul G. Allen Frontiers Group announced today the creation of an Allen Discovery Center for Human Brain Evolution at Boston Children’s Hospital and Harvard Medical School, to be led by Christopher A. Walsh, M.D., Ph.D.
Allen Institute for Brain Science releases new data and visualizations for Allen Brain Observatory
The Allen Institute for Brain Science today announced the release of new data and analysis tools for the Allen Brain Observatory: a highly standardized survey of cellular-level neuronal activity in the mouse visual system.
Paul G. Allen Frontiers Group gives $7.5M to studies on epigenetics, aging, evolution
GeekWire - Epigenetics, aging and microbial evolution: Those are the latest words in biomedical research for the Paul G. Allen Frontiers Group, backed up with $7.5 million in awards for five teams of scientists.
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