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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules

Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges
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news
Brain expansion brings bigger brains and clearer images, with the help of a diaper chemical
Clear, jelly-like mouse brains are the new gamechangers in neuroscience
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Allen Institute for Immunology partners with Lilly to better understand autoimmune disease
The Institute will use cutting-edge molecular profiling techniques and advanced bioinformatics tools to enable precision medicine in clinical trials...
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Scientific Overview | ExA-SPIM
A high-level explanation of the protocols necessary to implement the Expansion Selective Plane Illumination Microscopy (ExA–SPIM) pipeline
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New OpenScope projects aim to shed light on how we process our visual world
OpenScope is a shared neuroscience platform modeled after astronomy’s shared observatories
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Ananda Goldrath to Lead Allen Institute for Immunology
Dr. Ananda Goldrath will join as the Executive Vice President of the Allen Institute for Immunology in fall of 2023.
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Andy Hickl joins Allen Institute as Chief Technology Officer
Throughout his career, Hickl has led teams that used natural language processing, machine learning, artificial intelligence, and computer vision to tackle some of the world’s most important problems—from climate change and clean energy to biodiversity and global health.
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Long COVID’s long fallout
Patients share their experiences of ongoing, debilitating symptoms nearly 3 years after initial infection
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A new, custom-built microscope is capturing stunning views of the brain
‘ExA-SPIM’ microscope borrows from electronics industry to image incredible detail in an entire mouse brain
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Many long COVID patients suffer from persistent inflammation, study finds
Molecular footprint of the chronic condition could help guide clinical trial and treatment decisions
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SciShots: how to feed mini-organs
Scientists are making lab-grown mini-organs more lifelike by adding blood vessels
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Genes reveal surprising overlaps in brain diseases and disorders
Scientists find patterns in how disease-related genes switch on in the brain
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Hongkui Zeng elected to the National Academy of Sciences
Zeng was chosen for her contributions to understanding the cells and connections of the brain.
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media / Wired
A Huge New Data Set Pushes the Limits of Neuroscience
The Allen Institute’s release includes recordings from a whopping 300,000 mouse neurons. Now the challenge is figuring out what to do with all that data.
media / KOMO News
Seattle researchers lead ambitious project to map the human brain
We could be on the cusp of breakthrough treatments for brain diseases, from Alzheimer's Disease to depression and ADHD. Local scientists from the Allen Institute for Brain Science are spearheading a five-year project to map the human brain.
media / STAT News
NIH launches the next stage of its ‘human genome project’ for the brain
The National Institutes of Health on Thursday announced more than $600 million in fresh funding for an expansive and ongoing push to unravel the mysteries of the human brain, bankrolling efforts to create a detailed map of the whole brain, and devise new ways to target therapeutics and other molecules to specific brain cell populations.
media / Allen Institute
Ask Us Anything: Alzheimer’s Disease Brain Cell Atlas
Scientists from the Allen Institute and UW Medicine opened up about the Seattle Alzheimer’s Disease Brain Cell Atlas on Reddit
media / Fierce Biotech
In search of Alzheimer's drug targets, Allen Institute builds massive brain cell map
The initiative, called the Seattle Alzheimer’s Disease Brain Cell Atlas (SEA-AD), has released some of its first findings at the Alzheimer’s Association International Conference.
media / NPR
Alzheimer's researchers are looking beyond plaques and tangles for new treatments
Scientists say research into Alzheimer's needs to take a broader view of how the disease affects the brain — whether that's changes in the cortex or the role of inflammation.
media / Inside Precision Medicine
Data Trove Released by Seattle Alzheimer’s Disease Brain Cell Atlas
Neuroscientists at the Allen Institute for Brain Science and their collaborators have released their first research data set on Alzheimer’s disease, in which they categorized cell types based on gene activity. The team hope this approach could ultimately identify new targets for better therapies.
media / CBC
CBC: The Current for June 22, 2022
Claims that Google chat bot is sentient prompt wider questions, say experts; Russia’s invasion of Ukraine reaches four-month mark, with no end in sight; prescription heroin in Switzerland; and rip tide warning system aims to save lives
media / Allen Institute
Making the unknown known | 2021 Annual Report
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