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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges

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Cytiva licenses Allen Institute’s advanced machine learning technology to develop new cell imaging techniques
Strategic license to advance the field of 3D and live cell imaging
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Could treatments aimed at Alzheimer’s disease help combat COVID-19?
A team of cardiology researchers had a creative idea for a new way to treat dementia. Now they think it could help coronavirus patients too.
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A new approach to Alzheimer’s disease research
Most efforts to treat Alzheimer's disease simply haven't worked. That's why leading researchers in Seattle are teaming up with us to study early...
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Team science in the era of remote work
As the COVID-19 pandemic dictates physical distance and many scientists are working from home, how can teams pivot to pull off coordinated research...
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Old age changes the way blood accesses the brain
A new study in mice shows that contrary to longstanding dogma, blood proteins easily cross into the brain, but transport machinery breaks down with ag...
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The Leukemia & Lymphoma Society, The Mark Foundation for Cancer Research and The Paul G. Allen Frontiers Group Partner to Award $6.75M in New Grants to Drive the Next Wave of Novel Cancer Therapies
New “Blood Cancer Discoveries Grant Program” supported by a novel three-way collaboration
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Seattle researchers team up to build hi-res brain map of Alzheimer's disease
$40.5M NIH-funded project aims to pinpoint cells at the root of the progressive brain disease and home in on new therapeutic targets
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Cell Shorts | Lab-grown human skin holds promise for skin grafts
Researchers have succeeded in growing the most lifelike human skin in the lab to date. Allen Institute for Cell Science cell lines formed the basis...
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A new high-resolution, 3D map of the whole mouse brain
The reference atlas, years in the making, offers common ground to put neuroscience findings in context
brain science
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Science Matters | Redefining the immune system
"This is simply one of the best opportunities on the planet to really redefine how the immune system will be characterized in the future." Tom Bumol,...
immunology
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Seattle scientists launch $95 million AI biology effort
The Allen Institute, University of Washington, and Fred Hutch Cancer Center are launching a $95 million effort to use AI to design biology that doesn’t exist in nature. Called AI BioDesign and led scientifically by Nobel laureate David Baker and genome scientist Jay Shendure, the initiative will use AI models to propose new DNA sequences and biological molecules.

AI learns nature’s code: Allen Institute, UW and Fred Hutch launch $95M open science initiative
Three of Seattle’s top scientific institutions are launching a nearly $95 million research initiative that will generate data and train AI models to design proteins and genes that don’t exist in nature — sharing the results freely to help others develop new medicines and materials.

‘It’s going to come quicker than we think’: Parkinson’s advocate shares hope for treatment as Allen Institute launches AI-powered initiative
The institute has launched the Brain Health Accelerator, an international collaboration involving about 30 research organizations that will use artificial intelligence, human brain tissue and advanced cellular mapping to better understand diseases including Parkinson’s, Alzheimer’s disease, ALS, Huntington’s disease and Lewy body dementia.
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