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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges

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SciShots: the brain’s mysterious, multipurpose immune system
Microglial cells act as the brain’s waste disposal when healthy - can they be manipulated to protect against disease?
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Opening up about open science
In five words, more or less, what does open science mean to you?
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Look in the labs | Electron Microscopy Suite
See how researchers at the Allen Institute are using electron microscopy to map intricate connections between brain cells at ultra-high resolution.
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Look in the labs | Immunology
What makes the human immune system healthy, and what goes wrong in disease?
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Look in the labs | Neural Dynamics
How do different brain regions connect and communicate? Researchers at the Allen Institute for Neural Dynamics are 3D imaging whole mouse brains in...
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23 interns, 4 coffee machines, 1 summer: Through the eyes of this year’s cohort of budding science professionals
Allen Institute welcomes interns on-site for the first time since 2019 - these are some of their stories
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From 300,000 mouse neurons, scientists hope to glean how the brain drives behavior
New public dataset captures billions of electrical spikes from brains of animals trained to identify ‘oddball’ photos
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A prescription for exercise: Scientists want to help you find the best workout for your brain
Researchers are developing a fitness wearable to personalize exercise and lower the risks of dementia
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SciShots: clusters of Alzheimer’s cells
New data explores the cellular landscape of Alzheimer’s disease
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Seattle scientists launch $95 million AI biology effort
The Allen Institute, University of Washington, and Fred Hutch Cancer Center are launching a $95 million effort to use AI to design biology that doesn’t exist in nature. Called AI BioDesign and led scientifically by Nobel laureate David Baker and genome scientist Jay Shendure, the initiative will use AI models to propose new DNA sequences and biological molecules.

AI learns nature’s code: Allen Institute, UW and Fred Hutch launch $95M open science initiative
Three of Seattle’s top scientific institutions are launching a nearly $95 million research initiative that will generate data and train AI models to design proteins and genes that don’t exist in nature — sharing the results freely to help others develop new medicines and materials.

‘It’s going to come quicker than we think’: Parkinson’s advocate shares hope for treatment as Allen Institute launches AI-powered initiative
The institute has launched the Brain Health Accelerator, an international collaboration involving about 30 research organizations that will use artificial intelligence, human brain tissue and advanced cellular mapping to better understand diseases including Parkinson’s, Alzheimer’s disease, ALS, Huntington’s disease and Lewy body dementia.
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