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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges
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Allen Cell Methods: Cryopreservation of clonal human iPS cell lines in 96-well plates
To ensure researchers have success working with human induced pluripotent stem cell lines from the Allen Cell Catalog, Amanda Haupt, a research...
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How the gut keeps time - and keeps us healthy
New study identifies brain-intestine circadian signals that could underlie health problems related to night shift work and poor sleep
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Highest-Resolution Human Brain 'Parts List' To Date Lays Road Map to Better Treatments for Neurological and Psychiatric Disorders
Crucial differences discovered in human and mice brain cells could explain why many drugs that work in the lab don’t work in us
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This is what it’s like to donate your brain to science
Casey Schorr underwent invasive surgery to quell the epileptic seizures that were taking over his life. Now, a small piece of his brain tissue is...
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Virtual reality is helping neuroscientists better understand the brain
When Elise Shen goes to work, her morning starts much like that of anyone else with a desk job. She greets her coworkers. She fetches a cup of coffee....
brain science
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Simulations of life - in health and disease
Across many areas of biology, researchers are turning to virtual simulations to help ask and answer important questions.
brain science
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Machine learning toolkit lets biologists navigate their way through a 3D cell
In the world of computer vision, engineers need to build software that can recognize parts of an image or 3D visual field. Think, for example, a...
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These neurons are tied to one of multiple sclerosis’ most dramatic effects: Brain shrinkage
Multiple sclerosis begins with a maddening back and forth.
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Advancing Leading Edge Cancer Research in a $4.5 Million Collaboration
LLS, The Mark Foundation for Cancer Research and The Paul G. Allen Frontiers Group Join Forces to Advance Leading Edge Cancer Research
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Sorting neurons by their shape and activity to understand the elements making up the brain
To understand our brains, scientists need to know their components. This theme underlies a growing effort in neuroscience to define the different building blocks of the brain — its cells.
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Scientific American: First Atlas of Every Mouse Brain Cell Could Improve Neuro Disease Treatments
Neuroscientists have unveiled their most comprehensive and detailed map of cell types across the entire mouse brain, delivering the latest results of a six-year-long scientific effort in which Seattle’s Allen Institute has played a leading role.
Quanta Magazine: New Cell Atlases Reveal Untold Variety in the Brain and Beyond
(Photo credit: Peter Greenwood for Quanta Magazine.) Recent efforts to map every cell in the human body have researchers floored by unfathomable diversity, with many thousands of subtly different types of cells in the human brain alone.
Seattle Times: Research that brings AI into human cells will soon expand in Seattle
The Seattle Hub for Synthetic Biology, set to open in January, is a result of collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington that aims to build new technologies to record the history of our bodies’ cells.
Yahoo News: Allen Frontiers Group awards $10M to set up research center for neuroimmunology
The neuroimmunology research center will be led by Brian Kim of Mount Sinai and David Artis of Weill Cornell Medicine. They’ll bring together a multidisciplinary team to trace interactions between the nervous system and the immune system that occur at sites distant from the brain.
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