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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges
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A new discovery about ALS
Stem cell researcher Evangelos Kiskinis and his colleagues discovered a strange — literal — wrinkle in neurons from ALS patients. Allen Institute for Cell Science resources are helping them study these features in more detail.
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From brains to big data: How neuroscientists scale up research
A neuron’s months-long journey through the many sterile-gloved hands that make up a science pipeline
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Troy Torgerson | Transforming outcomes for patients
See how Troy Torgerson, Director of Experimental Immunology at the Allen Institute for Immunology, is leading cross-disciplinary teams in molecular...
immunology
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These visual neurons don’t work the way scientists thought, study finds
A new survey of the activity of nearly 60,000 neurons in the mouse visual system reveals how far we have to go to understand how the brain computes.
brain science
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These small proteins reveal a new kind of brain diversity
Endorphins and other neuropeptides vary widely between brain cell types and point to new possible targets for psychiatric drugs, study finds
brain science
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Data Stories | How bird brains help us understand our own
Erich Jarvis studies how vocal learning evolves. Allen Institute resources are helping him connect the dots from bird song to human speech.
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Out of Balance | Maria’s journey with melanoma
A fortuitous event led to an early diagnosis. Ten years later, her cancer journey is not over.
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The Paul G. Allen Frontiers Group Names New Allen Distinguished Investigators
Five new awardees will embark on stem cell and tissue research with the potential to impact human health
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How Hollywood’s latest animation technique is shedding new light on cell biology
A method developed to make more realistic computer graphics now forms the backbone of new 3D cell visualization tool
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Scientists find mouse neurons that are unique to male or female brains
Study linking behaviors with cells in an ancient section of the brain also pinpointed a neuron tied to social fear
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Puget Sound Business Journal: Seattle biotech research hub launches with big goals for growth, scientific advances
The Seattle Hub for Synthetic Biology is developing technology to monitor genomic changes in cells in real time, in turn showing cells' whole histories and the genetic causes of disease.
Inside Precision Medicine: How Single-Cell Omics is Revolutionizing Our View Of Neurobiology
(Photo credit: miakievy / Getty Images) The adult human brain is made up of billions of neurons and glial cells. Understanding the diversity of these cells and their distinctive gene-regulatory mechanisms is crucial for determining how the brain works and, in turn, for developing treatments for neurologic disorders
GeekWire: Inside the new Seattle Hub for Synthetic Biology, which uses DNA to ‘record biology over time’
(Photo credit: Charlotte Schubert) Researchers opened the doors Monday to the new Seattle Hub for Synthetic Biology, a collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington.
Science Friday: 3,000 Types Of Brain Cells Categorized In Massive Brain Cell Atlas
In October 2023, an international group of scientists released an impressively detailed cell atlas of the human brain, published in 21 papers in the journals Science, Science Advances and Science Translational Medicine.
STAT: Allen Institute CEO Rui Costa on mapping the brain and paying early-career scientists decent salaries
Mapping the billions of cells that make up the brain is a task mammoth enough to keep hundreds of researchers across continents busy for years. But it’s just one of several ambitious projects the Allen Institute is helping tackle.
Scientific American: First Atlas of Every Mouse Brain Cell Could Improve Neuro Disease Treatments
Neuroscientists have unveiled their most comprehensive and detailed map of cell types across the entire mouse brain, delivering the latest results of a six-year-long scientific effort in which Seattle’s Allen Institute has played a leading role.
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