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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges
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New study aims to answer pressing COVID-19 question: Why do some die while others don’t even know they are sick?
Seattle-area research organizations team up for a deep dive into patients’ immune responses to the novel coronavirus; results could contribute to...
immunology
news
These visual neurons catch what we might miss
When mice see faint objects approaching head on, certain neurons kick into gear - possibly to warn them
brain science
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Allen Institute for Cell Science announces leadership changes
Ruwanthi (Ru) Gunawardane, Ph.D., has been named Executive Director.
cell science
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Allen Institute announces 2020 Next Generation Leaders
Six early-career neuroscientists will participate in unique advisory council for the Institute
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The mammalian brain is built from many kinds of neurons. A new study reveals a holistic way to look at them.
Using a technique that simultaneously captures different kinds of features from each cell, researchers lay groundwork for a “family tree” of the brain.
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Mouse study uncovers links between unsung brain cells and Huntington’s disease - and possible path for human therapies
Astrocytes, once thought of as inert ‘brain glue,’ may turn out to be key players in Huntington’s and other neurodegenerative diseases
brain science
news
New cell line lets researchers use CRISPR to reversibly switch off genes
‘CRISPR interference’ technique enables study of basic cell biology and disease in human stem cells
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2 scientists win Nobel chemistry prize for gene-editing tool
Allen Distinguished Investigator Jennifer A. Doudna and her colleague Emmanuelle Charpentier won for developing CRISPR-cas9, a very simple technique for cutting a gene at a specific spot.
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Projects launch to map the nucleus, the information center of our cells
Teams from two divisions of the Allen Institute, the Allen Institute for Cell Science and the Allen Institute for Brain Science, are participating in...
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An automated pipeline for understanding how the brain is wired
To truly understand the brain, we need a roadmap of how it’s wired. The gold standard for studying the cellular architecture and the connectivity of...
brain science
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Scientific American: First Atlas of Every Mouse Brain Cell Could Improve Neuro Disease Treatments
Neuroscientists have unveiled their most comprehensive and detailed map of cell types across the entire mouse brain, delivering the latest results of a six-year-long scientific effort in which Seattle’s Allen Institute has played a leading role.
Quanta Magazine: New Cell Atlases Reveal Untold Variety in the Brain and Beyond
(Photo credit: Peter Greenwood for Quanta Magazine.) Recent efforts to map every cell in the human body have researchers floored by unfathomable diversity, with many thousands of subtly different types of cells in the human brain alone.
Seattle Times: Research that brings AI into human cells will soon expand in Seattle
The Seattle Hub for Synthetic Biology, set to open in January, is a result of collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington that aims to build new technologies to record the history of our bodies’ cells.
Yahoo News: Allen Frontiers Group awards $10M to set up research center for neuroimmunology
The neuroimmunology research center will be led by Brian Kim of Mount Sinai and David Artis of Weill Cornell Medicine. They’ll bring together a multidisciplinary team to trace interactions between the nervous system and the immune system that occur at sites distant from the brain.
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