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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges
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Brain scientists unveil wiring diagram containing 200,000 cells and nearly half billion connections in tiny piece of a mouse's brain
Detailed map captures 3D shapes of neurons and their synapses in stunning detail and is open to community for neuroscience and machine learning...
brain science
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To understand human cells, scientists look beyond genes
Deep dive into detailed images of human heart cells uncovers a disconnect between gene expression and cell structure
cell science
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Science in Sixty | Shannon Reynolds
Figuring out how to transport live brain tissue from the operating room to the lab is challenging to say the least. In our latest Science in Sixty,...
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Study maps all the types of neurons across two major structures of the mouse brain
Cell-type parts list of the mouse neocortex and the hippocampal formation yields new information about how the mammalian brain evolved and develops
brain science
news
Science in Sixty | Brian Lee
Brian Lee, Ph.D., Senior Scientist at the Allen Institute for Brain Science, shares his journey from rebellious teen to crisis counselor to neuroscientist.
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New technique explores the ins and outs of our immune cells
Method that captures 3 different characteristics of individual human cells at once can shed light on aging and disease.
immunology
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Allen Institute and BioMarin team up to develop gene therapies for rare brain diseases.
The collaboration leverages technologies intended to target gene expression to specific cells within the central nervous system
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your life history is written in your cells' mutations
New study traces developmental history of the human body using small differences in DNA between each of our cells
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Science in Sixty | Ru Gunawardane
Ru Gunawardane, Ph.D., is the Executive Director of the Allen Institute for Cell Science, where she leads a team of scientists, engineers, artists and other experts, all working together to understand how our cells function.
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Allen Institute adds leading health care attorney to board of directors
Carla DewBerry brings expertise in health care law and background in nonprofit philanthropic boards to the research organization’s governing board
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Scientific American: First Atlas of Every Mouse Brain Cell Could Improve Neuro Disease Treatments
Neuroscientists have unveiled their most comprehensive and detailed map of cell types across the entire mouse brain, delivering the latest results of a six-year-long scientific effort in which Seattle’s Allen Institute has played a leading role.
Quanta Magazine: New Cell Atlases Reveal Untold Variety in the Brain and Beyond
(Photo credit: Peter Greenwood for Quanta Magazine.) Recent efforts to map every cell in the human body have researchers floored by unfathomable diversity, with many thousands of subtly different types of cells in the human brain alone.
Seattle Times: Research that brings AI into human cells will soon expand in Seattle
The Seattle Hub for Synthetic Biology, set to open in January, is a result of collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington that aims to build new technologies to record the history of our bodies’ cells.
Yahoo News: Allen Frontiers Group awards $10M to set up research center for neuroimmunology
The neuroimmunology research center will be led by Brian Kim of Mount Sinai and David Artis of Weill Cornell Medicine. They’ll bring together a multidisciplinary team to trace interactions between the nervous system and the immune system that occur at sites distant from the brain.
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