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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges
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New study aims to answer pressing COVID-19 question: Why do some die while others don’t even know they are sick?
Seattle-area research organizations team up for a deep dive into patients’ immune responses to the novel coronavirus; results could contribute to...
immunology
news
These visual neurons catch what we might miss
When mice see faint objects approaching head on, certain neurons kick into gear - possibly to warn them
brain science
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Allen Institute for Cell Science announces leadership changes
Ruwanthi (Ru) Gunawardane, Ph.D., has been named Executive Director.
cell science
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Allen Institute announces 2020 Next Generation Leaders
Six early-career neuroscientists will participate in unique advisory council for the Institute
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The mammalian brain is built from many kinds of neurons. A new study reveals a holistic way to look at them.
Using a technique that simultaneously captures different kinds of features from each cell, researchers lay groundwork for a “family tree” of the brain.
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Mouse study uncovers links between unsung brain cells and Huntington’s disease - and possible path for human therapies
Astrocytes, once thought of as inert ‘brain glue,’ may turn out to be key players in Huntington’s and other neurodegenerative diseases
brain science
news
New cell line lets researchers use CRISPR to reversibly switch off genes
‘CRISPR interference’ technique enables study of basic cell biology and disease in human stem cells
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2 scientists win Nobel chemistry prize for gene-editing tool
Allen Distinguished Investigator Jennifer A. Doudna and her colleague Emmanuelle Charpentier won for developing CRISPR-cas9, a very simple technique for cutting a gene at a specific spot.
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Projects launch to map the nucleus, the information center of our cells
Teams from two divisions of the Allen Institute, the Allen Institute for Cell Science and the Allen Institute for Brain Science, are participating in...
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An automated pipeline for understanding how the brain is wired
To truly understand the brain, we need a roadmap of how it’s wired. The gold standard for studying the cellular architecture and the connectivity of...
brain science
news
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KIRO Radio: Breakthroughs in Synthetic Biology
(Interview starts 11:35 in) Troy McDiarmid from the Seattle Center for Synthetic Biology describes the innovative research underway to create cellular recorders that will track the full life histories of human cells to better understand disease.
Puget Sound Business Journal: Seattle biotech research hub launches with big goals for growth, scientific advances
The Seattle Hub for Synthetic Biology is developing technology to monitor genomic changes in cells in real time, in turn showing cells' whole histories and the genetic causes of disease.
Inside Precision Medicine: How Single-Cell Omics is Revolutionizing Our View Of Neurobiology
(Photo credit: miakievy / Getty Images) The adult human brain is made up of billions of neurons and glial cells. Understanding the diversity of these cells and their distinctive gene-regulatory mechanisms is crucial for determining how the brain works and, in turn, for developing treatments for neurologic disorders
GeekWire: Inside the new Seattle Hub for Synthetic Biology, which uses DNA to ‘record biology over time’
(Photo credit: Charlotte Schubert) Researchers opened the doors Monday to the new Seattle Hub for Synthetic Biology, a collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington.
Science Friday: 3,000 Types Of Brain Cells Categorized In Massive Brain Cell Atlas
In October 2023, an international group of scientists released an impressively detailed cell atlas of the human brain, published in 21 papers in the journals Science, Science Advances and Science Translational Medicine.
STAT: Allen Institute CEO Rui Costa on mapping the brain and paying early-career scientists decent salaries
Mapping the billions of cells that make up the brain is a task mammoth enough to keep hundreds of researchers across continents busy for years. But it’s just one of several ambitious projects the Allen Institute is helping tackle.
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