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From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules

Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges
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Hundreds of small molecules known as neuromodulators might influence how we learn
New models that capture how the brain retains information could also improve machine learning
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Allen Institute announces Rui Costa as next President and Chief Executive Officer
The Allen Institute today named Rui Costa, D.V.M., Ph.D., as its next president and chief executive officer.
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Making the unknown known | 2021 Annual Report
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Allen Institute announces 2021 Next Generation Leaders
Six early-career neuroscientists will participate in unique advisory council for the Institute
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Announcing the Allen Institute for Neural Dynamics, a new neuroscience division of the Allen Institute
New Institute will study how the brain’s circuitry and activity give rise to complex behavior, decision making and memory
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Now in stunning, whole-brain resolution: neurons
A new study traced the 3D shape of more than 1700 complete mouse neurons across the entire brain
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Living brain donors are helping us better understand our own neurons - including those potentially linked to Alzheimer’s disease
As part of an international effort to map cell types in the brain, scientists identified increased diversity of neurons in regions of the human brain that expanded during our evolution
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New insights about evolution of human brain region that controls voluntary movement, including rare, large neurons vulnerable in ALS
Is our brain like that of a mouse or a monkey? New study aims to find our cellular similarities - and key differences
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An ultra detailed map of the brain region that controls movement, from mice to monkeys to humans
Hundreds of neuroscientists built a ‘parts list’ of the motor cortex, laying groundwork to map the whole brain and better understand brain disease...
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These rare human neurons generate electrical signals in two different cellular parts
With brain tissue samples donated by surgery patients come detailed descriptions of certain rare types of human cells - including new findings about...
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Q&A with the Allen Institute for Immunology’s first employee
Ernie Coffey started his career in science with a bang. It was 1997 and he landed a job at one of the institutes participating in the sequencing of...
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Sped-up evolution may have molded the human brain by slowing neuron growth
Quickly evolving stretches of DNA unique to humans are important for brain development, a new study finds
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media / MyNorthwest / KIRO Radio
KIRO Radio: Breakthroughs in Synthetic Biology
(Interview starts 11:35 in) Troy McDiarmid from the Seattle Center for Synthetic Biology describes the innovative research underway to create cellular recorders that will track the full life histories of human cells to better understand disease.
media / Puget Sound Business Journal
Puget Sound Business Journal: Seattle biotech research hub launches with big goals for growth, scientific advances
The Seattle Hub for Synthetic Biology is developing technology to monitor genomic changes in cells in real time, in turn showing cells' whole histories and the genetic causes of disease.
media / Inside Precision Medicine
Inside Precision Medicine: How Single-Cell Omics is Revolutionizing Our View Of Neurobiology
(Photo credit: miakievy / Getty Images) The adult human brain is made up of billions of neurons and glial cells. Understanding the diversity of these cells and their distinctive gene-regulatory mechanisms is crucial for determining how the brain works and, in turn, for developing treatments for neurologic disorders
media / GeekWire
GeekWire: Inside the new Seattle Hub for Synthetic Biology, which uses DNA to ‘record biology over time’
(Photo credit: Charlotte Schubert) Researchers opened the doors Monday to the new Seattle Hub for Synthetic Biology, a collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington.
media / The Scientist
The Scientist: A Cell-by-Cell Map of the Entire Mouse Brain
This comprehensive map laid the foundation for the next stage of investigations, such as scaling up efforts to chart nonhuman primates and human brains.
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media / ABC News
ABC News: Scientists take on 'moonshot' project mapping the human brain in hopes of fighting disease
Researchers say this could lead to more targeted treatment approaches.
media / Fox 13 Seattle
Q13 FOX: Learn why with PacSci: How muscles, nerves, and the brain works together
The Pacific Science Center is celebrating Brain Awareness Week with its BrainFest event on March 16.
media / Science Friday
Science Friday: 3,000 Types Of Brain Cells Categorized In Massive Brain Cell Atlas
In October 2023, an international group of scientists released an impressively detailed cell atlas of the human brain, published in 21 papers in the journals Science, Science Advances and Science Translational Medicine.
media / STAT News
STAT: Allen Institute CEO Rui Costa on mapping the brain and paying early-career scientists decent salaries
Mapping the billions of cells that make up the brain is a task mammoth enough to keep hundreds of researchers across continents busy for years. But it’s just one of several ambitious projects the Allen Institute is helping tackle.
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