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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges

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Allen Institute for Immunology partners with Lilly to better understand autoimmune disease
The Institute will use cutting-edge molecular profiling techniques and advanced bioinformatics tools to enable precision medicine in clinical trials...
immunology
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Scientific Overview | ExA-SPIM
A high-level explanation of the protocols necessary to implement the Expansion Selective Plane Illumination Microscopy (ExA–SPIM) pipeline
neural dynamics
video
New OpenScope projects aim to shed light on how we process our visual world
OpenScope is a shared neuroscience platform modeled after astronomy’s shared observatories
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news

Ananda Goldrath to Lead Allen Institute for Immunology
Dr. Ananda Goldrath will join as the Executive Vice President of the Allen Institute for Immunology in fall of 2023.
immunology
news

Andy Hickl joins Allen Institute as Chief Technology Officer
Throughout his career, Hickl has led teams that used natural language processing, machine learning, artificial intelligence, and computer vision to tackle some of the world’s most important problems—from climate change and clean energy to biodiversity and global health.
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Long COVID’s long fallout
Patients share their experiences of ongoing, debilitating symptoms nearly 3 years after initial infection
immunology
news

A new, custom-built microscope is capturing stunning views of the brain
‘ExA-SPIM’ microscope borrows from electronics industry to image incredible detail in an entire mouse brain
neural dynamics
video

Many long COVID patients suffer from persistent inflammation, study finds
Molecular footprint of the chronic condition could help guide clinical trial and treatment decisions
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SciShots: how to feed mini-organs
Scientists are making lab-grown mini-organs more lifelike by adding blood vessels
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science images

Genes reveal surprising overlaps in brain diseases and disorders
Scientists find patterns in how disease-related genes switch on in the brain
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KIRO Radio: Breakthroughs in Synthetic Biology
(Interview starts 11:35 in) Troy McDiarmid from the Seattle Center for Synthetic Biology describes the innovative research underway to create cellular recorders that will track the full life histories of human cells to better understand disease.
Puget Sound Business Journal: Seattle biotech research hub launches with big goals for growth, scientific advances
The Seattle Hub for Synthetic Biology is developing technology to monitor genomic changes in cells in real time, in turn showing cells' whole histories and the genetic causes of disease.
Inside Precision Medicine: How Single-Cell Omics is Revolutionizing Our View Of Neurobiology
(Photo credit: miakievy / Getty Images) The adult human brain is made up of billions of neurons and glial cells. Understanding the diversity of these cells and their distinctive gene-regulatory mechanisms is crucial for determining how the brain works and, in turn, for developing treatments for neurologic disorders
GeekWire: Inside the new Seattle Hub for Synthetic Biology, which uses DNA to ‘record biology over time’
(Photo credit: Charlotte Schubert) Researchers opened the doors Monday to the new Seattle Hub for Synthetic Biology, a collaboration between the Allen Institute, the Chan Zuckerberg Initiative and the University of Washington.
Science Friday: 3,000 Types Of Brain Cells Categorized In Massive Brain Cell Atlas
In October 2023, an international group of scientists released an impressively detailed cell atlas of the human brain, published in 21 papers in the journals Science, Science Advances and Science Translational Medicine.
STAT: Allen Institute CEO Rui Costa on mapping the brain and paying early-career scientists decent salaries
Mapping the billions of cells that make up the brain is a task mammoth enough to keep hundreds of researchers across continents busy for years. But it’s just one of several ambitious projects the Allen Institute is helping tackle.
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