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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
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AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules

Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges
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These visual neurons don’t work the way scientists thought, study finds
A new survey of the activity of nearly 60,000 neurons in the mouse visual system reveals how far we have to go to understand how the brain computes.
brain science
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These small proteins reveal a new kind of brain diversity
Endorphins and other neuropeptides vary widely between brain cell types and point to new possible targets for psychiatric drugs, study finds
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Data Stories | How bird brains help us understand our own
Erich Jarvis studies how vocal learning evolves. Allen Institute resources are helping him connect the dots from bird song to human speech.
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Out of Balance | Maria’s journey with melanoma
A fortuitous event led to an early diagnosis. Ten years later, her cancer journey is not over.
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The Paul G. Allen Frontiers Group Names New Allen Distinguished Investigators
Five new awardees will embark on stem cell and tissue research with the potential to impact human health
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How Hollywood’s latest animation technique is shedding new light on cell biology
A method developed to make more realistic computer graphics now forms the backbone of new 3D cell visualization tool
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Scientists find mouse neurons that are unique to male or female brains
Study linking behaviors with cells in an ancient section of the brain also pinpointed a neuron tied to social fear
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Allen Institute debuts new window into brain cell communication
The Allen Institute today released its first - and the world’s largest - dataset of electrical brain activity gathered using Neuropixels, a new...
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New grants to study the aging brain and build better tools to access brain cells
NIH funding will support an atlas of aging mouse brain cell types and a toolkit to light up specific brain cell types
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Data Stories | How a weight loss drug acts on the brain
Scientists at a pharmaceutical company want to know how the drug they developed for weight management affects the brain. Allen Institute resources are...
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A computational challenge to help developmental biology
Q&A with the scientists and organizers behind a new competition to use machine learning to reconstruct an entire animal’s developmental lineage
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Three collaborative studies launch on ‘OpenScope,’ a shared observatory for neuroscience
2019 projects will tackle Alzheimer’s disease, motion detection, and how the brain processes contextual information
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media / GeekWire
Tech Moves: Allen Institute names new VP
Julie Harris has been appointed vice president of The Paul G. Allen Frontiers Group at the Seattle-based Allen Institute.
media / The Scientist
Charting the Human Immune Health Atlas
Every individual’s immune system is distinct and changes over time, affecting their health and disease response. Recently, researchers mapped human immune cells to explore what defines a healthy immune system across different ages.
media / The Transmitter
The Transmitter: Expanding set of viral tools targets almost any brain cell type
Harmless viruses that encase short noncoding DNA elements called enhancers enable cell-type-specific gene delivery across the central nervous system in rodents and primates.
media / NPR
NPR: Timeline shows what happens to different brain cells as Alzheimer’s progresses
An analysis of brains at various stages of Alzheimer's found that neurons called inhibitory neurons are the first to be affected by the disease.
media / Fox News
Fox News: New Alzheimer’s research reveals ‘quiet’ phase of the disease, before symptoms appear
Researchers led by the Allen Institute for Brain Science in Seattle and University of Washington Medicine have identified cellular changes in the brains of people with the disease — and a timeline of when they occur.
media / Newsweek
Newsweek: Alzheimer's Hidden 'Early' Brain Damage Phase Revealed by Neuroscientists
Alzheimer's disease damages the brain before any symptoms begin to appear, new research suggests. This is part of a new two-step model of Alzheimer's progression, which features an early "silent" stage of brain damage.
media / New York Times
New York Times: After a Decade, Scientists Unveil Fly Brain in Stunning Detail
(Photo credit: Tyler Sloan for FlyWire, Princeton University) Scientists have mapped out how 140,000 neurons are wired in the brain of the fruit fly, Drosophila melanogaster.
media / Nature
Nature: Largest brain map ever reveals fruit fly’s neurons in exquisite detail
(Photo credit: Tyler Sloan and Amy Sterling for FlyWire, Princeton University) “This is a huge deal,” says Clay Reid, a neurobiologist at the Allen Institute for Brain Science
media / New Scientist
NewScientist: Map of the immune system changing with age may help optimise vaccines
Our immune cells change a lot as the decades progress, which could explain why we become more susceptible to certain conditions
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