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stories from the front lines of discovery
From scientific breakthroughs to new open‑source tools, the Allen Institute’s work is reshaping how science is done—and who it’s for. Explore the latest news, stories, and highlights from across our research, partnerships, and open science efforts.
AI BioDesign accelerator combines experimental biology and artificial intelligence to learn nature’s design rules
Researchers from the Allen Institute, University of Washington, and Fred Hutch Cancer Center, supported by Fund for Science and Technology, will build open AI models, datasets, and tools to accelerate biological design for health, sustainability, and other global challenges

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Allen Institute announces Rui Costa as next President and Chief Executive Officer
The Allen Institute today named Rui Costa, D.V.M., Ph.D., as its next president and chief executive officer.
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Allen Institute announces 2021 Next Generation Leaders
Six early-career neuroscientists will participate in unique advisory council for the Institute
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Announcing the Allen Institute for Neural Dynamics, a new neuroscience division of the Allen Institute
New Institute will study how the brain’s circuitry and activity give rise to complex behavior, decision making and memory
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Now in stunning, whole-brain resolution: neurons
A new study traced the 3D shape of more than 1700 complete mouse neurons across the entire brain
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Living brain donors are helping us better understand our own neurons - including those potentially linked to Alzheimer’s disease
As part of an international effort to map cell types in the brain, scientists identified increased diversity of neurons in regions of the human brain that expanded during our evolution
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New insights about evolution of human brain region that controls voluntary movement, including rare, large neurons vulnerable in ALS
Is our brain like that of a mouse or a monkey? New study aims to find our cellular similarities - and key differences
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An ultra detailed map of the brain region that controls movement, from mice to monkeys to humans
Hundreds of neuroscientists built a ‘parts list’ of the motor cortex, laying groundwork to map the whole brain and better understand brain disease...
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These rare human neurons generate electrical signals in two different cellular parts
With brain tissue samples donated by surgery patients come detailed descriptions of certain rare types of human cells - including new findings about...
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Q&A with the Allen Institute for Immunology’s first employee
Ernie Coffey started his career in science with a bang. It was 1997 and he landed a job at one of the institutes participating in the sequencing of...
immunology
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Sped-up evolution may have molded the human brain by slowing neuron growth
Quickly evolving stretches of DNA unique to humans are important for brain development, a new study finds
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Brain scientists unveil wiring diagram containing 200,000 cells and nearly half billion connections in tiny piece of a mouse's brain
Detailed map captures 3D shapes of neurons and their synapses in stunning detail and is open to community for neuroscience and machine learning...
brain science
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Seattle scientists launch $95 million AI biology effort
The Allen Institute, University of Washington, and Fred Hutch Cancer Center are launching a $95 million effort to use AI to design biology that doesn’t exist in nature. Called AI BioDesign and led scientifically by Nobel laureate David Baker and genome scientist Jay Shendure, the initiative will use AI models to propose new DNA sequences and biological molecules.

AI learns nature’s code: Allen Institute, UW and Fred Hutch launch $95M open science initiative
Three of Seattle’s top scientific institutions are launching a nearly $95 million research initiative that will generate data and train AI models to design proteins and genes that don’t exist in nature — sharing the results freely to help others develop new medicines and materials.

‘It’s going to come quicker than we think’: Parkinson’s advocate shares hope for treatment as Allen Institute launches AI-powered initiative
The institute has launched the Brain Health Accelerator, an international collaboration involving about 30 research organizations that will use artificial intelligence, human brain tissue and advanced cellular mapping to better understand diseases including Parkinson’s, Alzheimer’s disease, ALS, Huntington’s disease and Lewy body dementia.
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