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Allen Institute discoveries, innovations, and open-source resources are transforming the scientific landscape and making progress possible. Read on for the latest news and highlights.

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First-ever BrainFest inspires young minds at Pacific Science Center


Allen Institute and Pacific Science Center partnership kicks off with a cerebral celebration

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illustration with outline of brain over a maze


How the brain learns to find its next reward: Warm, warmer, hot!


Rewards don’t just reinforce a specific action—they quickly change the whole pattern of how we behave

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neurons firing or not firing in response to the presence of a visual mask


Delving into the science of a mystifying optical illusion: visual masking


A new study sheds light on how our brains perceive — or fail to perceive — what we see

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Researchers eagerly gather around gelatin substance involved with tissue expansion.


Brain expansion brings bigger brains and clearer images, with the help of a diaper chemical


Clear, jelly-like mouse brains are the new gamechangers in neuroscience

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Scientific Overview | ExA-SPIM


A high-level explanation of the protocols necessary to implement the Expansion Selective Plane Illumination Microscopy (ExA–SPIM) pipeline

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Image of ExA-SPIM an imaging tool developed by the Allen Institute for Neural Dynamics


A new, custom-built microscope is capturing stunning views of the brain


‘ExA-SPIM’ microscope borrows from electronics industry to image incredible detail in an entire mouse brain

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Allen Institute 2022 Next Generation Leaders. Top row (from left to right): Constantina Theofanopoulou, Heather Snell, Karthik Shekhar. Bottom row (from left to right) Kauê Machado,Leena Ali Ibrahim, Tahra Eissa.


Allen Institute Announces 2022 Next Generation Leaders


Six early-career neuroscientists will help guide research into the complexities of the mammalian brain

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Lab Notes | Cracking the code of addiction


Neuroscientists at the Allen Institute and the University of North Carolina are working to crack the biology of reward and addiction. Hear about their...

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Scientist holding up research equipment


Look in the labs | Neural Dynamics


How do different brain regions connect and communicate? Researchers at the Allen Institute for Neural Dynamics are 3D imaging whole mouse brains in...

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Image of a glowing mouse brain

Science Images

SciShots: The 3D network inside a mouse’s brain


Scientists are piecing together the puzzle of the brain using light-sheet microscopy

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Illustration by Jenny Burns / Allen Institute


Why is the human brain so difficult to understand? We asked 4 neuroscientists.


Thoughts, memories, sensations — why are we still in the dark about how they work?

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Researchers setting up an experiment at the Allen Institute for Neural Dynamics


Announcing the Allen Institute for Neural Dynamics, a new neuroscience division of the Allen Institute


New Institute will study how the brain’s circuitry and activity give rise to complex behavior, decision making and memory

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