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Allen Institute discoveries, innovations, and open-source resources are transforming the scientific landscape and making progress possible. Read on for the latest news and highlights.

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The Paul G. Allen Frontiers Group Announces 16 New Allen Distinguished Investigators

12.15.2022

$10M in research funding will support cutting-edge projects in protein lifespan and nutrient sensing

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These brain cells named for stars contribute to Alzheimer’s

11.03.2022

Mouse study reveals many new types of cells known as astrocytes and narrows their role in neurodegenerative disease

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The Allen Institute’s bicycling group on their evening cycle in South Lake Union. Photo by Erik Dinnel / Allen Institute

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A prescription for exercise: Scientists want to help you find the best workout for your brain

08.09.2022

Researchers are developing a fitness wearable to personalize exercise and lower the risks of dementia

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DNA’s molecular wrinkles: Why you might be older or younger than you think

08.03.2022

‘Epigenetic clocks’ vary with disease and even by organ, but scientists are still trying to understand why

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DNA Typewriter keeps a record of cells’ long histories

07.21.2022

Molecular recording device could be used to trace cell-by-cell growth of an entire animal

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SciShots: Glowing muscles of the comb jelly

05.27.2022

Biologists are studying the neurons and muscle cells of the ctenophore, a type of sea jelly that is the sister group to all other animals

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SciShots: How the brain plugs leaks

04.22.2022

A delicate molecular dance maintains the blood-brain barrier, protecting the brain while allowing transport of necessary resources

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A new technique developed by AHA-Allen Initiative-funded researchers at the Stanford University School of Medicine is shining light on the blood vessels that supply the brain. Illustration by Valentina Galata.

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A map of all our brains’ blood vessel cells finds new clues to Alzheimer’s disease

02.14.2022

Scientists release the first cell-by-cell atlas of the human blood-brain barrier.

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SciShots: A cell’s fate

02.11.2022

Synthetic biology is helping scientists understand development

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The Paul G. Allen Frontiers Group announces 23 new Allen Distinguished Investigators

02.09.2022

$15.5M in research funding will support cutting-edge projects in mammalian synthetic biology, the neuroscience of under-studied animals, and tiny...

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SciShots: Mini-brains

01.14.2022

Organoids are miniature versions of organs grown in the lab from stem cells — in many cases, from human stem cells.

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$20M awards fund centers’ studies of human brain evolution, animal development

12.02.2021

Two Allen Discovery Centers enter their next phase of discovery, poised to address large questions about biology

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News from The Paul G. Allen Frontiers Group: December 2021

12.02.2021

Highlights include: $20M in funding to support frontier science, how sped-up evolution may have molded the human brain, upcoming events and more.

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Sped-up evolution may have molded the human brain by slowing neuron growth

09.09.2021

Quickly evolving stretches of DNA unique to humans are important for brain development, a new study finds

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News from The Paul G. Allen Frontiers Group: June 2021

06.23.2021

Highlights include a new study by the Allen Discovery Center for Human Brain Evolution, a Science in Sixty video featuring Kathryn Richmond, and more.

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Your life history is written in your cells’ mutations

04.13.2021

New study traces developmental history of the human body using small differences in DNA between each of our cells

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How old is this bat? A new DNA-based test can tell.

03.23.2021

Molecular clock links immunity, cancer suppression to bats’ extraordinarily long lives; new method could also help conservation efforts

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News from The Paul G. Allen Frontiers Group: March 2021

03.18.2021

New open calls for ADI awards, Immunometabolism ADIs announced, and more

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A microscopy image of a section of a mouse colon, showing a protective layer of mucus in green that is often disrupted in human inflammatory bowel disease, or IBD. A team of newly announced Allen Distinguished Investigators is investigating how immune cells, metabolism, gut bacteria and people’s environments contribute to disease variability among IBD patients. Image courtesy of Katharine Ng, Tropini Lab, University of British Columbia.

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New Allen Distinguished Investigators will tackle unanswered questions about metabolism and the immune system

02.03.2021

Awards announced today by The Paul G. Allen Frontiers Group will fund research in health, disease, and technology development all centered on the...

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Naked mole rats don’t show signs of old age, but their DNA says otherwise

01.23.2021

‘Queens’ of the rodent colonies age even more slowly than the extremely long-lived naked mole rat

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