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The Transmitter: Split gene therapy delivers promise in mice modeling Dravet syndrome

Apr 11, 2025

A potential new gene therapy for Dravet syndrome increases survival and prevents seizures, according to initial tests in mice, a new study shows. The...

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Scientists on the Neural Coding team at the Allen Institute

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Associated Press: Scientists map part of a mouse’s brain that’s so complex it looks like a galaxy

Apr 11, 2025

Thanks to a mouse watching clips from “The Matrix,” scientists have created the largest functional map of a brain to date – a diagram of the...

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All of these images show a subset of more than 1,000 of the 120,000 brain cells (neuron + glia) reconstructed in the MICRONS project. Each reconstructed neuron is a different random color. In some of the images, a subset of the neurons have been rendered as glowing in different ways to represent the fact that this dataset includes functional recordings from a subset of neurons.

In the News

New York Times: An Advance in Brain Research That Was Once Considered Impossible

Apr 11, 2025

Scientists achieved “a milestone” by charting the activity and structure of 200,000 cells in a mouse brain and their 523 million connections.

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John Mich in the lab at the Allen Institute

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Gene Therapy Tested in Mice Offers New Hope for People with Dravet Syndrome

Mar 20, 2025

Scientists from the Allen Institute and Seattle Children’s Research Institute have announced a breakthrough in the development of gene replacement...

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Boaz Levi in the lab

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Groundbreaking gene therapy research in Washington could lead to treat children living with severe epilepsy

Mar 20, 2025

Scientists at the Allen Institute have made a major breakthrough in research for people living with Dravet Syndrome, which is a rare and debilitating...

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Boaz Levi and John Mich in the lab of the Allen Institute in Seattle, WA

In the News

Breakthrough gene therapy in Seattle offers hope for children with epilepsy

Mar 20, 2025

Scientists at the Allen Institute for Brain Science are working on a promising gene therapy that could offer a life-saving treatment for children...

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GeekWire: Seattle Hub for Synthetic Biology lands $10M to support ‘DNA Typewriter’ technology

Mar 6, 2025

The Seattle Hub for Synthetic Biology is receiving a $10 million grant to support the training of new scientists and the launch of biotech startups...

GeekWire
Visualization of the human brain.

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Cell ‘fingerprints’ identify distinct cortical networks

Mar 3, 2025

These networks align with different assemblages of cells, a finding that could reveal how cellular diversity influences brain function, according to a...

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A visualization of a large-scale model of a mouse visual cortex brain circuit, built at the Allen Institute and containing 230,000 neuron building-block models, recently published in the journal Neuron. Image courtesy of Sergey Gratiy, Ph.D.

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News

The last two-author neuroscience paper?

Mar 3, 2025

Author lists on papers have ballooned, and it’s getting hard to discern contribution.

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Learn How the Brain Ages at the Cellular Level

Mar 3, 2025

Join Dr. Kelly Jin, a scientist at the Allen Institute for Brain Science, as she discusses new research on how our brains change as we age.

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Science Programs at Allen Institute