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A new study from the Allen Institute compares human brain cells’ molecular features to those of the marmoset monkey and mouse in a region of the brain that controls movement, the primary motor cortex. Using a technique known as single-cell transcriptomics, the researchers compared the suite of genes each individual brain cell switches on, across thousands of cells from each of the three species. Shown here, transcriptomic data clustered by type of brain cell, in the human (left), marmoset monkey (middle), and mouse brain (right)

In the News

New brain maps could help the search for Alzheimer’s treatments

Oct 6, 2021

NPR - An international consortium involving hundreds of scientists has unveiled highly detailed maps of the brain area that controls movement.

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Researcher seated at a table analyzing data on a laptop

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Share methods through visual and digital protocols

Jul 21, 2021

Nature - Documenting experimental methods ensures reproducibility and accountability, and there are innovative ways to disseminate and update them.

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Human brain cells

In the News

Allen Institute Announces Complete Genetic Map of the Human Brain

Apr 30, 2021

The Wall Street Journal - Scientists funded by Microsoft Corp. co-founder Paul Allen unveiled a $55 million computerized atlas of the human brain...

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Alzheimer's Brain Sections

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Alzheimer’s Researchers Go Back To Basics To Find The Best Way Forward

Jun 25, 2020

NPR - Three research institutions in Seattle have joined forces to study how Alzheimer's disease takes root in the brain.

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Researchers Created a 3-D Map of 100 Million Cells in the Mouse Brain

May 13, 2020

Smithsonian Magazine - Neuroscientists have been using the tool since 2017 to pinpoint where exactly their data are coming from

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Hundreds of spinning cells against a black background

In the News

Science-ing from home

Mar 26, 2020

Nature - In the first of two articles about laboratory closures triggered by COVID-19, scientists affected by the shutdowns outline the tools they are...

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In the News

Epilepsy treatment side effect: New insights about the brain

Feb 11, 2020

AP News - Though Genette Hofmann is still using her brain, last month she donated a bit of it — to science.

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Scientists routinely cure brain disorders in mice but not us. A new study helps explain why

Aug 21, 2019

STAT - Lab mice endure a lot for science, but there’s often one (temporary) compensation: near-miraculous recovery from diseases that kill people.

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What can mice teach Allen Institute researchers about treating brain disorders in humans?

Aug 21, 2019

The Seattle Times - Psychiatric drugs meant for humans have been tested on mice for years. The two species’ brains have similar cellular structures....

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